日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Using Next Generation Chemiluminescent Probes to Improve the Plasmodium falciparum in vitro Parasite Reduction Ratio (PRR) Assay

利用新一代化学发光探针改进恶性疟原虫体外寄生虫减少率（PRR）检测

期刊:ACS Infectious Diseases
影响因子:3.8
doi:10.1021/acsinfecdis.5c00924
Hellingman, Angela; Göttle, Nele Lara; Walz, Annabelle; Brancucci, Nicolas Michel Beat; Wittlin, Sergio; Mäser, Pascal; Rottmann, Matthias
微生物学
发表日期：2026
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Design and optimization of simplified inhibitors targeting Escherichia coli and Klebsiella pneumoniae IspE

设计和优化针对大肠杆菌和肺炎克雷伯菌 IspE 的简化抑制剂

期刊:RSC Medicinal Chemistry
影响因子:3.6
doi:10.1039/d5md00874c
Walsh, Danica J; Hamid, Rawia; Giele, Tim; Reiling, Norbert; Rottmann, Matthias; Hamed, Mostafa M; Hirsch, Anna K H
肺炎
发表日期：2026
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Integrative preclinical strategy for pharmacokinetic profiling and candidate selection of 3-hydroxypropanamidines: a promising antimalarial class

3-羟基丙脒类药物（一种有前景的抗疟药）的药代动力学分析和候选药物筛选的综合临床前策略

期刊:Malaria Journal
影响因子:3
doi:10.1186/s12936-026-05837-9
Moritz, Alena; Hirn-Derksen, Bastian; Klein, Saskia; Held, Jana; Wittlin, Sergio; Rottmann, Matthias; Kurz, Thomas; Burckhardt, Bjoern B
发表日期：2026
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A Novel Antimalarial Agent that Inhibits Protein Synthesis in Plasmodium falciparum

一种新型抗疟药，可抑制恶性疟原虫的蛋白质合成

期刊:Angewandte Chemie-International Edition
影响因子:16.9
doi:10.1002/anie.202514085
Bravo, Patricia; Diamanti, Eleonora; Hamed, Mostafa M; Bizzarri, Lorenzo; Wiedemar, Natalie; Passecker, Armin; Brancucci, Nicolas M B; Albisetti, Anna; Gumpp, Christin; Illarionov, Boris; Fischer, Markus; Witschel, Matthias; Schehl, Tobias; Hahne, Hannes; Mäser, Pascal; Rottmann, Matthias; Hirsch, Anna K H
发表日期：2025
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An all-in-one pipeline for the in vitro discovery and in vivo testing of Plasmodium falciparum malaria transmission blocking drugs.

用于体外发现和体内测试恶性疟原虫疟疾传播阻断药物的一体化流程

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-62014-3
Brancucci Nicolas M B, Gumpp Christin, van Gemert Geert-Jan, Yu Xiao, Passecker Armin, Nardella Flore, Thommen Basil T, Chambon Marc, Turcatti Gerardo, Halby Ludovic, Blasco Benjamin, Duffey Maëlle, Arimondo Paola B, Bousema Teun, Scherf Artur, Leroy Didier, Kooij Taco W A, Rottmann Matthias, Voss Till S
其它
药物研究
发表日期：2025
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Positive Charge in an Antimalarial Compound Unlocks Broad-Spectrum Antibacterial Activity

抗疟化合物中的正电荷可释放广谱抗菌活性

期刊:JACS Au
影响因子:8.7
doi:10.1021/jacsau.4c00935
Braun-Cornejo, Maria; Platteschorre, Mitchell; de Vries, Vincent; Bravo, Patricia; Sonawane, Vidhisha; Hamed, Mostafa M; Haupenthal, Jörg; Reiling, Norbert; Rottmann, Matthias; Piet, Dennis; Maas, Peter; Diamanti, Eleonora; Hirsch, Anna K H
发表日期：2025
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Structure-Activity Relationships of 3-Hydroxypropanamidines (HPAs) with Potent In Vivo Antimalarial Activity

3-羟基丙脒类化合物（HPAs）的构效关系及其强效的体内抗疟活性

期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/acs.jmedchem.5c01337
Klein, Saskia; Moritz, Alena; Pessanha de Carvalho, Lais; Knaab, Tanja C; Lungerich, Beate; Meyer, Lukas; Sandström, Jona; Thibaud, Jessica L; de Villiers, Katherine A; Fidock, David A; Wittlin, Sergio; Rottmann, Matthias; Held, Jana; Burckhardt, Bjoern B; Kurz, Thomas
发表日期：2025
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The Importance of Murine Models in Determining In Vivo Pharmacokinetics, Safety, and Efficacy in Antimalarial Drug Discovery

小鼠模型在抗疟药物研发中确定体内药代动力学、安全性和有效性的重要性

期刊:Pharmaceuticals
影响因子:4.8
doi:10.3390/ph18030424
Adebayo, Glory; Ayanda, Opeyemi I; Rottmann, Matthias; Ajibaye, Olusola S; Oduselu, Gbolahan; Mulindwa, Julius; Ajani, Olayinka O; Aina, Oluwagbemiga; Mäser, Pascal; Adebiyi, Ezekiel
发表日期：2025
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Design, Synthesis and Antiplasmodial Activities of a Library of Fluorine-Based 3-Benzylmenadiones

氟基3-苄基甲萘醌类化合物库的设计、合成及其抗疟活性

期刊:Molecules
影响因子:4.6
doi:10.3390/molecules30112446
Roignant, Matthieu; Richard, Jimmy; Donzel, Maxime; Rottmann, Matthias; Mäser, Pascal; Davioud-Charvet, Elisabeth
发表日期：2025
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Drug Interaction Studies of Cabamiquine:Ganaplacide Combination against Hepatic Plasmodium berghei

卡巴米喹：加那普拉西联合用药对抗伯氏疟原虫肝感染的药物相互作用研究

期刊:ACS Infectious Diseases
影响因子:3.8
doi:10.1021/acsinfecdis.4c00563
Gal, Isabella Ramella; Demarta-Gatsi, Claudia; Fontinha, Diana; Arez, Francisca; Wicha, Sebastian G; Rottmann, Matthias; Nunes-Cabaço, Helena; Blais, Johanne; Jain, Jay Prakash; Lakshminarayana, Suresh B; Brito, Catarina; Prudêncio, Miguel; Alves, Paula M; Spangenberg, Thomas
炎症/感染
发表日期：2025
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