日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

ENX-101, a GABA(A) receptor α2,3,5-selective positive allosteric modulator, displays antiseizure effects in rodent seizure and epilepsy models.

ENX-101 是一种 GABA(A) 受体 α2,3,5 选择性正向变构调节剂,在啮齿动物癫痫模型中显示出抗癫痫作用

Serrats Jordi, Vadodaria Krishna C, Brubaker William, Barker-Haliski Melissa, White H Steve, Evrard Alexis, Roucard Corinne, Taylor Eve, Vanover Kimberly E, Cunningham Stephen, Sudarsan Vikram, Rogawski Michael A

Evoked responses to single pulse electrical stimulation reveal impaired striatal excitability in a rat model of Parkinson's disease

单脉冲电刺激诱发的反应揭示了帕金森病大鼠模型纹状体兴奋性受损

Gronlier, Eloïse; Volle, Julien; Coizet, Véronique; Paccard, Antoine; Habermacher, Chloé; Roche, Yann; Roucard, Corinne; Duveau, Venceslas; David, Olivier

Pronounced antiseizure activity of the subtype-selective GABA(A) positive allosteric modulator darigabat in a mouse model of drug-resistant focal epilepsy

在药物难治性局灶性癫痫小鼠模型中,亚型选择性GABA(A)正向变构调节剂darigabat表现出显著的抗癫痫活性

Gurrell, Rachel; Iredale, Philip; Evrard, Alexis; Duveau, Venceslas; Ruggiero, Céline; Roucard, Corinne

Pronounced antiepileptic activity of the subtype-selective GABA(A) -positive allosteric modulator PF-06372865 in the GAERS absence epilepsy model

在GAERS失神癫痫模型中,亚型选择性GABA(A)正向变构调节剂PF-06372865表现出显著的抗癫痫活性

Duveau, Venceslas; Buhl, Derek L; Evrard, Alexis; Ruggiero, Céline; Mandé-Niedergang, Betty; Roucard, Corinne; Gurrell, Rachel

Methodological standards and interpretation of video-electroencephalography in adult control rodents. A TASK1-WG1 report of the AES/ILAE Translational Task Force of the ILAE

成年对照啮齿动物视频脑电图的方法学标准和结果解读。国际抗癫痫联盟(ILAE)AES/ILAE转化工作组TASK1-WG1报告

Kadam, Shilpa D; D'Ambrosio, Raimondo; Duveau, Venceslas; Roucard, Corinne; Garcia-Cairasco, Norberto; Ikeda, Akio; de Curtis, Marco; Galanopoulou, Aristea S; Kelly, Kevin M

Chronic administration of atypical antipsychotics improves behavioral and synaptic defects of STOP null mice

长期服用非典型抗精神病药物可改善STOP基因敲除小鼠的行为和突触缺陷。

Delotterie, David; Ruiz, Geoffrey; Brocard, Jacques; Schweitzer, Annie; Roucard, Corinne; Roche, Yann; Suaud-Chagny, Marie-Françoise; Bressand, Karine; Andrieux, Annie

Modulation of the major histocompatibility complex class II-associated peptide repertoire by human histocompatibility leukocyte antigen (HLA)-DO

人类组织相容性白细胞抗原 (HLA)-DO 对主要组织相容性复合体 II 类相关肽库的调节

M van Ham, M van Lith, B Lillemeier, E Tjin, U Grüneberg, D Rahman, L Pastoors, K van Meijgaarden, C Roucard, J Trowsdale, T Ottenhoff, D Pappin, J Neefjes