日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Identification of four mechanisms of toxicity for per- and polyfluoroalkyl substances through transcriptomic profiling in human liver spheroids exposed to 24 PFAS

通过对暴露于24种全氟烷基和多氟烷基物质(PFAS)的人类肝球体进行转录组分析,鉴定出四种PFAS的毒性机制。

Addicks, Greggory C; Rowan-Carroll, Andrea; Leingartner, Karen; Williams, Andrew; Meier, Mathew J; Lorusso, Luigi; Yauk, Carole L; Atlas, Ella

Deciphering per- and polyfluoroalkyl substances mode of action: comparative gene expression analysis in human liver spheroids

解析全氟和多氟烷基物质的作用机制:人肝球体中的基因表达比较分析

Andrea Rowan-Carroll ,Matthew J Meier ,Carole L Yauk ,Andrew Williams ,Karen Leingartner ,Lauren Bradford ,Luigi Lorusso ,Ella Atlas

Impacts of Inorganic Arsenic Exposure on Genetic Stability of Human Mesenchymal Stromal Cells

无机砷暴露对人类间充质干细胞遗传稳定性的影响

Beal, Marc A; Coughlan, Melanie; Nunnikhoven, Andrée; Corbane, Reena; Cummings-Lorbetskie, Cathy; Rowan-Carroll, Andrea; Sharma, Tanvi; Williams, Andrew; Lavoie, Jessie R; Stalker, Andrew; Mohapatra, Asish; Meier, Matthew J

House dust-derived mixtures of organophosphate esters alter the phenotype, function, transcriptome, and lipidome of KGN human ovarian granulosa cells

源自室内灰尘的有机磷酸酯混合物会改变KGN人卵巢颗粒细胞的表型、功能、转录组和脂质组。

Xiaotong Wang ,Andrea Rowan-Carroll ,Matthew J Meier ,Carole L Yauk ,Michael G Wade ,Bernard Robaire ,Barbara F Hales

Toxicological Mechanisms and Potencies of Organophosphate Esters in KGN Human Ovarian Granulosa Cells as Revealed by High-throughput Transcriptomics

高通量转录组学揭示有机磷酸酯在KGN人卵巢颗粒细胞中的毒理机制和毒性

Xiaotong Wang ,Andrea Rowan-Carroll ,Matthew J Meier ,Andrew Williams ,Carole L Yauk ,Barbara F Hales ,Bernard Robaire

In vitro transcriptomic analyses reveal pathway perturbations, estrogenic activities, and potencies of data-poor BPA alternative chemicals

体外转录组分析揭示了缺乏数据的双酚A替代化学物质的通路扰动、雌激素活性和效力

Geronimo Matteo ,Karen Leingartner ,Andrea Rowan-Carroll ,Matthew Meier ,Andrew Williams ,Marc A Beal ,Matthew Gagné ,Reza Farmahin ,Shamika Wickramasuriya ,Anthony J F Reardon ,Tara Barton-Maclaren ,J Christopher Corton ,Carole L Yauk ,Ella Atlas

Per- and polyfluoroalkyl substances (PFAS) in mixtures show additive effects on transcriptomic points of departure in human liver spheroids

混合物中的全氟和多氟烷基物质(PFAS)对人类肝球体转录组起始点表现出累加效应

Gregory C Addicks ,Andrea Rowan-Carroll ,Anthony J F Reardon ,Karen Leingartner ,Andrew Williams ,Matthew J Meier ,Ivy Moffat ,Richard Carrier ,Luigi Lorusso ,Barbara A Wetmore ,Carole L Yauk ,Ella Atlas

Dataset on DNA methylation and gene expression changes induced by 5-aza-2'-deoxycytidine in Syrian golden hamster fetal cell cultures

5-氮杂-2'-脱氧胞苷诱导叙利亚金仓鼠胎儿细胞培养物中DNA甲基化和基因表达变化的数据集

Matthew J Meier ,Cathy Cummings-Lorbetskie ,Andrea Rowan-Carroll ,Daniel Desaulniers

Integrated Genotoxicity Testing of three anti-infective drugs using the TGx-DDI transcriptomic biomarker and high-throughput CometChip® assay in TK6 cells

使用 TGx-DDI 转录组生物标志物和高通量 CometChip® 检测法在 TK6 细胞中对三种抗感染药物进行综合基因毒性测试

Julie K Buick, Andrea Rowan-Carroll, Rémi Gagné, Andrew Williams, Renxiang Chen, Heng-Hong Li, Albert J Fornace Jr, Christy Chao, Bevin P Engelward, Roland Frötschl, Heidrun Ellinger-Ziegelbauer, Syril D Pettit, Jiri Aubrecht, Carole L Yauk

Paternal exposure to benzo(a)pyrene induces genome-wide mutations in mouse offspring

父本暴露于苯并[a]芘会导致小鼠后代出现全基因组突变

Marc A Beal ,Matthew J Meier ,Andrew Williams ,Andrea Rowan-Carroll ,Rémi Gagné ,Sarah J Lindsay ,Tomas Fitzgerald ,Matthew E Hurles ,Francesco Marchetti ,Carole L Yauk