日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Identity, functional consequences, and context effects of amino acids inserted during suppression of CFTR nonsense mutations

CFTR无义突变抑制过程中插入的氨基酸的身份、功能后果和背景效应

Thrasher, Kari; Chen, Jianguo; Fu, Lianwu; Benson, Dominique; Ekstrom, Jenna; Hargett, Audra A; Renfrow, Matthew B; Rowe, Steven M; Keeling, Kim M; Bedwell, David M

Hyaluronan Ameliorates Viral Pneumonia in Mice and Humans by Inhibiting Transcription Factor E2F1

透明质酸通过抑制转录因子E2F1改善小鼠和人类的病毒性肺炎

Stober, Vandy P; Trempus, Carol S; Galdi, Flavia; Martin, Negin P; Gladwell, Wesley; Cronce, Michael; Cox, Jeffery S; Keasling, Jay D; Budzik, Jonathan; Chen, Shih-Heng; Sakamachi, Yosuke; Li, Jian-Liang; McGee, Christopher A; Zaccaro, Daniel J; Der, Jane S; Tucker, Charles J; Scappini, Erica; Campos Gomez, Javier; Rowe, Steven M; Cowman, Mary K; Barkauskas, Christina E; Lee, Patty J; Markovetz, Matthew R; Button, Brian; Hill, David B; Erxleben, Dorothea A; Hall, Adam R; Liu, Jian; Xu, Yongmei; Pedone, Claudio; Antonelli Incalzi, Raffaele; Matalon, Sadis; Savani, Rashmin C; Garantziotis, Stavros

Identification of small molecules that enhance aminoglycoside-mediated suppression of CFTR and NF1 nonsense mutations.

鉴定能增强氨基糖苷类药物对 CFTR 和 NF1 无义突变抑制作用的小分子。

Sammons Joshua, Chen Jianguo, Thrasher Kari, Fu Lianwu, Du Ming, Wen Hui, Bostwick J Robert, Vinson Paige, Moukha-Chafiq Omar, Augelli-Szafran Corinne, Keeling Kim M, Wallis Deeann, Kesterson Robert A, Rowe Steven M, Bedwell David M

AirSeg: Learnable Interconnected Attention Framework for Robust Airway Segmentation

AirSeg:用于稳健气道分割的可学习互连注意力框架

Krishnan, Chetana; Hussain, Shah; Stanford, Denise; Sthanam, Venkata; Bodduluri, Sandeep; Raju, S Vamsee; Rowe, Steven M; Kim, Harrison

Ivacaftor for Chronic Obstructive Pulmonary Disease: Results from a Phase 2, Randomized Controlled Trial

伊伐卡托治疗慢性阻塞性肺疾病:一项 II 期随机对照试验的结果

Vijaykumar, Kadambari; Solomon, George M; Guimbellot, Jennifer; Acosta, Edward P; Bhambhavni, Pradeep G; White, Sharon; Kim, Harrison; Raju, S Vamsee; Rasmussen, Lawrence W; Harris, Necole; Liu, Bo; Hathorne, Heather; Rowe, Steven M; Dransfield, Mark T

A ferret model demonstrates sustained fibrosis, restrictive physiology, and airway proximalization.

雪貂模型显示持续性纤维化、限制性生理和气道近端化。

Peabody Lever Jacelyn E, Li Qian, Pavelkova Nikoleta, Hussain Shah S, Bakshi Sayan, Ren Janna Q, Jones Luke I, Jadhav Kajal, Kennemur Jared P, Weupe Mason, Campos-Gomez Javier, Tang Liping, Peabody Lever Jeremie M, Wang Dezhi, Stanford Denise D, Foote Jeremy B, Harrod Kevin S, Kim Harrison, Phillips Scott E, Rowe Steven M

ACE-2 blockade and TMPRSS2 inhibition mitigate SARS-CoV-2 severity following cigarette smoke exposure in airway epithelial cells in vitro.

ACE-2 阻断和 TMPRSS2 抑制可减轻体外气道上皮细胞暴露于香烟烟雾后 SARS-CoV-2 的严重程度

Hussain Shah S, Libby Emily Falk, Peabody Lever Jacelyn E, Tipper Jennifer L, Phillips Scott E, Mazur Marina, Li Qian, Campos-Gómez Javier, Harrod Kevin S, Rowe Steven M

Fecal microbiota changes in people with cystic fibrosis after 6 months of elexacaftor/tezacaftor/ivacaftor: Findings from the promise study

囊性纤维化患者接受 elexacaftor/tezacaftor/ivacaftor 治疗 6 个月后粪便微生物群的变化:来自 Promise 研究的发现

Duong, Jennifer T; Hayden, Hillary S; Verster, Adrian J; Pope, Christopher E; Miller, Carson; Kelsi Penewit; Salipante, Stephen J; Rowe, Steven M; Solomon, George M; Nichols, David; Kelly, Andrea; Schwarzenberg, Sarah Jane; Freedman, Steven D; Hoffman, Lucas R

Glycemia and Insulin Secretion in Cystic Fibrosis 2 Years After Elexacaftor/Tezacaftor/Ivacaftor: PROMISE-ENDO

囊性纤维化患者接受 Elexacaftor/Tezacaftor/Ivacaftor 治疗 2 年后血糖和胰岛素分泌情况:PROMISE-ENDO 研究

Chan, Christine L; Shirley Bezerra, Meghan; Stefanovski, Darko; Gallop, Robert J; Walega, Rachel; Donaldson, Scott H; Frederick, Carla A; Freedman, Steven D; Gelfond, Daniel; Hoffman, Lucas R; Narkewicz, Michael R; Rowe, Steven M; Sagel, Scott D; Schwarzenberg, Sarah Jane; Solomon, George M; Stalvey, Michael S; Kelly, Andrea

Aspergillus fumigatus is influenced by mucus accumulation, airway inflammation and cystic fibrosis transmembrane conductance regulator function

烟曲霉的生长受黏液积聚、气道炎症和囊性纤维化跨膜传导调节因子功能的影响。

Poore, T Spencer; Nguyen, Anh; Schaefers, Levi; Solomonik, Anna; Rieglers, Ashleigh; Leal, Sixto M Jr; Rowe, Steven M; Birket, Susan