Discovery and Characterization of Potent, Efficacious, Orally Available Antimalarial Plasmepsin X Inhibitors and Preclinical Safety Assessment of UCB7362
高效、有效、口服的抗疟疾血浆蛋白酶X抑制剂的发现与表征及UCB7362的临床前安全性评估
期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/acs.jmedchem.2c01336
Lowe, Martin A; Cardenas, Alvaro; Valentin, Jean-Pierre; Zhu, Zhaoning; Abendroth, Jan; Castro, Jose L; Class, Reiner; Delaunois, Annie; Fleurance, Renaud; Gerets, Helga; Gryshkova, Vitalina; King, Lloyd; Lorimer, Donald D; MacCoss, Malcolm; Rowley, Julian H; Rosseels, Marie-Luce; Royer, Leandro; Taylor, Richard D; Wong, Melanie; Zaccheo, Oliver; Chavan, Vishal P; Ghule, Gokul A; Tapkir, Bapusaheb K; Burrows, Jeremy N; Duffey, Maëlle; Rottmann, Matthias; Wittlin, Sergio; Angulo-Barturen, Iñigo; Jiménez-Díaz, María Belén; Striepen, Josefine; Fairhurst, Kate J; Yeo, Tomas; Fidock, David A; Cowman, Alan F; Favuzza, Paola; Crespo-Fernandez, Benigno; Gamo, Francisco Javier; Goldberg, Daniel E; Soldati-Favre, Dominique; Laleu, Benoît; de Haro, Teresa
