Elaiophylin triggers paraptosis and preferentially kills ovarian cancer drug-resistant cells by inducing MAPK hyperactivation
Elaiophylin 通过诱导 MAPK 过度活化来触发副凋亡并优先杀死卵巢癌耐药细胞
期刊:Signal Transduction and Targeted Therapy
影响因子:40.8
doi:10.1038/s41392-022-01131-7
Guan-Nan Li #, Xue-Jiao Zhao #, Zhen Wang #, Meng-Shi Luo, Shen-Nan Shi, Dan-Mei Yan, Hua-Yi Li, Jia-Hao Liu, Yang Yang, Jia-Hong Tan, Ze-Yu Zhang, Ru-Qi Chen, Hui-Ling Lai, Xiao-Yuan Huang, Jian-Feng Zhou, Ding Ma, Yong Fang, Qing-Lei Gao
信号转导
肿瘤
卵巢癌
其它细胞
Apoptosis
MAPK/ERK
