日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Structural basis for substrate specificity and MSMEG_0435-0436 binding by the mycobacterial long-chain acyl-CoA carboxylase complex.

分枝杆菌长链酰基辅酶A羧化酶复合物的底物特异性和MSMEG_0435-0436结合的结构基础。

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2530575123
Liang Yingke, Bueler Stephanie A, Rubinstein John L
多发性硬化症
发表日期：2026
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Structural basis for EtfD-mediated coupling of β-oxidation and the respiratory chain in mycobacteria

分枝杆菌中 EtfD 介导的 β-氧化与呼吸链偶联的结构基础

期刊:EMBO Journal
影响因子:8.3
doi:10.1038/s44318-026-00726-y
Courbon, Gautier M; Makarov, Vadim; Cole, Stewart T; Schnapinger, Dirk; Ehrt, Sabine; Rubinstein, John L
发表日期：2026
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PRRC2A, PRRC2B and PRRC2C are Stress Granule Proteins that Promote Translation Through Association with the eIF3 complex

PRRC2A、PRRC2B 和 PRRC2C 是应激颗粒蛋白，它们通过与 eIF3 复合物结合来促进翻译。

期刊:
影响因子:
doi:10.64898/2026.02.24.707808
Huang, Jie Qi; Kadijk, Eileigh; Schreiber, Karl J; Liu, Zi Hao; Chiang, Rachel W; Zhang, Zhixin; Guttman, Kevin; Huang, Tian Hao; Almeida, Sylvia M T; Zhulyn, Olena; Moses, Alan; Forman-Kay, Julie D; Rubinstein, John L; Youn, Ji-Young
发表日期：2026
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The dynamic and heterogeneous structure of the non-canonical inflammasome

非经典炎症小体的动态和异质性结构

期刊:
影响因子:
doi:10.64898/2026.04.15.718739
Sever, Alexander I M; Aramini, James M; Bonin, Jeffrey P; Zhao, Huaying; Wang, Hanlin; Rubinstein, John L; Schuck, Peter; Kay, Lewis E
炎性小体
炎性小体
炎症/感染
免疫/内分泌
炎症
发表日期：2026
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Conformational changes in the motor ATPase CpaF facilitate a rotary mechanism of Tad pilus assembly

马达ATPase CpaF的构象变化促进了Tad菌毛组装的旋转机制。

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-59009-5
Yen, Ian Y; Whitfield, Gregory B; Rubinstein, John L; Burrows, Lori L; Brun, Yves V; Howell, P Lynne
发表日期：2025
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Structural elucidation of full-length Pfs48/45 in complex with potent monoclonal antibodies isolated from a naturally exposed individual

从自然暴露个体中分离出的强效单克隆抗体与全长 Pfs48/45 复合物的结构解析

期刊:Nature Structural & Molecular Biology
影响因子:10.1
doi:10.1038/s41594-025-01532-6
Kucharska, Iga; Ivanochko, Danton; Hailemariam, Sophia; Inklaar, Maartje R; Kim, Hee Ryung; Teelen, Karina; Stoter, Rianne; van de Vegte-Bolmer, Marga; van Gemert, Geert-Jan; Semesi, Anthony; McLeod, Brandon; Ki, Ahyoung; Lee, Won-Kyu; Rubinstein, John L; Jore, Matthijs M; Julien, Jean-Philippe
单克隆抗体
发表日期：2025
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De novo design of potent inhibitors of clostridial family toxins

从头设计高效梭菌毒素抑制剂

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2509329122
Ragotte, Robert J; Liang, Huazhu; Tam, John; Miletic, Sean; Berman, Jacob M; Palou, Roger; Weidle, Connor; Li, Zhijie; Glögl, Matthias; Beilhartz, Greg L; Carr, Kenneth D; Borst, Andrew J; Coventry, Brian; Wang, Xinru; Rubinstein, John L; Tyers, Mike; Schramek, Daniel; Melnyk, Roman A; Baker, David
发表日期：2025
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Cryo-EM of native membranes reveals an intimate connection between the Krebs cycle and aerobic respiration in mycobacteria.

冷冻电镜观察天然膜揭示了分枝杆菌中克雷布斯循环与有氧呼吸之间的密切联系

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2423761122
Di Trani Justin M, Yu Jiacheng, Courbon Gautier M, Lobez Rodriguez Ana Paula, Cheung Chen-Yi, Liang Yingke, Coupland Claire E, Bueler Stephanie A, Cook Gregory M, Brzezinski Peter, Rubinstein John L
微生物学
发表日期：2025
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Design, Synthesis, and Biological Evaluation of Mono- and Diamino-Substituted Squaramide Derivatives as Potent Inhibitors of Mycobacterial Adenosine Triphosphate (ATP) Synthase

单氨基和二氨基取代的方酰胺衍生物作为结核分枝杆菌腺苷三磷酸（ATP）合成酶的强效抑制剂的设计、合成和生物学评价

期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/acs.jmedchem.5c02284
Palme, Paul R; Grover, Shipra; Abdelaziz, Rana; Mann, Lea; Kany, Andreas M; Ouologuem, Lina; Bartel, Karin; Sonnenkalb, Lindsay; Reiling, Norbert; Hirsch, Anna K H; Schnappinger, Dirk; Rubinstein, John L; Imming, Peter; Richter, Adrian
发表日期：2025
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Structure of endogenous Pfs230:Pfs48/45 in complex with potent malaria transmission-blocking antibodies.

内源性 Pfs230:Pfs48/45 与强效疟疾传播阻断抗体的复合物结构

期刊:
影响因子:
doi:10.1101/2025.02.14.638310
Bekkering Ezra T, Yoo Randy, Hailemariam Sophia, Heide Fabian, Ivanochko Danton, Jackman Matthew, Proellochs Nicholas I, Stoter Rianne, van Gemert Geert-Jan, Maeda Ayana, Yuguchi Takaaki, Wanders Oscar T, van Daalen Renate C, Inklaar Maartje R, Andrade Carolina M, Jansen Pascal W T C, Vermeulen Michiel, Bousema Teun, Takashima Eizo, Rubinstein John L, Kooij Taco W A, Jore Matthijs M, Julien Jean-Philippe
其它
发表日期：2025
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