日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

FAST: a 5-minute assay for measuring fibrinolytic activation

FAST:一种用于测量纤溶激活的5分钟检测方法

Law, Ruby H P; Xie, Nian

Structural basis for uPAR binding to an antibody developed for targeted cancer therapy. Mechanistic insights into flexibility, ligand recognition, and molecular imaging

uPAR与靶向癌症治疗抗体结合的结构基础。对柔性、配体识别和分子成像的机制性见解

Anane, Rex F; Kumari, Anni; Venugopal, Hari; Trépout, Sylvain; Whisstock, James C; Engelholm, Lars H; Law, Ruby H P; Ploug, Michael

A mechanism for hereditary angioedema caused by a methionine-379-to-lysine substitution in kininogens

激肽原中甲硫氨酸-379 被赖氨酸取代引起的遗传性血管性水肿的机制

Dickeson, S Kent; Kumar, Sunil; Sun, Mao-Fu; Litvak, Maxim; He, Tracey Z; Phillips, Dennis R; Roberts, Elijah T; Feener, Edward P; Law, Ruby H P; Gailani, David

Proteoform-Resolved Profiling of Plasminogen Activation Reveals Novel Abundant Phosphorylation Site and Primary N-Terminal Cleavage Site

纤溶酶原激活的蛋白质组学解析分析揭示了一个新的丰富磷酸化位点和主要的N端切割位点

Cramer, Dario A T; Yin, Victor; Caval, Tomislav; Franc, Vojtech; Yu, Dingyi; Wu, Guojie; Lloyd, Gordon; Langendorf, Christopher; Whisstock, James C; Law, Ruby H P; Heck, Albert J R

Macrocyclic Inhibitors Targeting the Prime Site of the Fibrinolytic Serine Protease Plasmin

靶向纤溶丝氨酸蛋白酶纤溶酶主要结合位点的环状抑制剂

Wiedemeyer, Simon J A; Wu, Guojie; Lang-Henkel, Heike; Whisstock, James C; Law, Ruby H P; Steinmetzer, Torsten

A High-Throughput Small-Angle X-ray Scattering Assay to Determine the Conformational Change of Plasminogen

一种用于测定纤溶酶原构象变化的高通量小角X射线散射分析方法

Quek, Adam J; Cowieson, Nathan P; Caradoc-Davies, Tom T; Conroy, Paul J; Whisstock, James C; Law, Ruby H P

A mechanism for hereditary angioedema caused by a lysine 311-to-glutamic acid substitution in plasminogen

纤溶酶原中赖氨酸 311 位点被谷氨酸取代引起的遗传性血管性水肿的机制

S Kent Dickeson, Sunil Kumar, Mao-Fu Sun, Bassem M Mohammed, Dennis R Phillips, James C Whisstock, Adam J Quek, Edward P Feener, Ruby H P Law, David Gailani

Model for surface-dependent factor XII activation: the roles of factor XII heavy chain domains

表面依赖性因子 XII 激活模型:因子 XII 重链结构域的作用

Aleksandr Shamanaev, Ivan Ivanov, Mao-Fu Sun, Maxim Litvak, Priyanka Srivastava, Bassem M Mohammed, Rabia Shaban, Ashoka Maddur, Ingrid M Verhamme, Owen J T McCarty, Ruby H P Law, David Gailani

Effective targeting of intact and proteolysed CDCP1 for imaging and treatment of pancreatic ductal adenocarcinoma

有效靶向完整和蛋白水解的 CDCP1 用于胰腺导管腺癌的成像和治疗

Thomas Kryza, Tashbib Khan, Simon Puttick, Chao Li, Kamil A Sokolowski, Brian Wc Tse, Tahleesa Cuda, Nicholas Lyons, Madeline Gough, Julia Yin, Ashleigh Parkin, Elena I Deryugina, James P Quigley, Ruby H P Law, James C Whisstock, Andrew D Riddell, Andrew P Barbour, David K Wyld, Paul A Thomas, Steph

The cryo-EM structure of the acid activatable pore-forming immune effector Macrophage-expressed gene 1

酸激活成孔免疫效应物巨噬细胞表达基因 1 的低温电子显微镜结构

Siew Siew Pang, Charles Bayly-Jones, Mazdak Radjainia, Bradley A Spicer, Ruby H P Law, Adrian W Hodel, Edward S Parsons, Susan M Ekkel, Paul J Conroy, Georg Ramm, Hariprasad Venugopal, Phillip I Bird, Bart W Hoogenboom, Ilia Voskoboinik, Yann Gambin, Emma Sierecki, Michelle A Dunstone, James C Whiss