日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A mechanism for hereditary angioedema caused by a lysine 311-to-glutamic acid substitution in plasminogen

纤溶酶原中赖氨酸 311 位点被谷氨酸取代引起的遗传性血管性水肿的机制

S Kent Dickeson, Sunil Kumar, Mao-Fu Sun, Bassem M Mohammed, Dennis R Phillips, James C Whisstock, Adam J Quek, Edward P Feener, Ruby H P Law, David Gailani

Model for surface-dependent factor XII activation: the roles of factor XII heavy chain domains

表面依赖性因子 XII 激活模型:因子 XII 重链结构域的作用

Aleksandr Shamanaev, Ivan Ivanov, Mao-Fu Sun, Maxim Litvak, Priyanka Srivastava, Bassem M Mohammed, Rabia Shaban, Ashoka Maddur, Ingrid M Verhamme, Owen J T McCarty, Ruby H P Law, David Gailani

Effective targeting of intact and proteolysed CDCP1 for imaging and treatment of pancreatic ductal adenocarcinoma

有效靶向完整和蛋白水解的 CDCP1 用于胰腺导管腺癌的成像和治疗

Thomas Kryza, Tashbib Khan, Simon Puttick, Chao Li, Kamil A Sokolowski, Brian Wc Tse, Tahleesa Cuda, Nicholas Lyons, Madeline Gough, Julia Yin, Ashleigh Parkin, Elena I Deryugina, James P Quigley, Ruby H P Law, James C Whisstock, Andrew D Riddell, Andrew P Barbour, David K Wyld, Paul A Thomas, Steph

The cryo-EM structure of the acid activatable pore-forming immune effector Macrophage-expressed gene 1

酸激活成孔免疫效应物巨噬细胞表达基因 1 的低温电子显微镜结构

Siew Siew Pang, Charles Bayly-Jones, Mazdak Radjainia, Bradley A Spicer, Ruby H P Law, Adrian W Hodel, Edward S Parsons, Susan M Ekkel, Paul J Conroy, Georg Ramm, Hariprasad Venugopal, Phillip I Bird, Bart W Hoogenboom, Ilia Voskoboinik, Yann Gambin, Emma Sierecki, Michelle A Dunstone, James C Whiss

Tranexamic acid is an active site inhibitor of urokinase plasminogen activator

氨甲环酸是尿激酶纤溶酶原激活剂的活性位点抑制剂

Guojie Wu, Blake A Mazzitelli, Adam J Quek, Matthew J Veldman, Paul J Conroy, Tom T Caradoc-Davies, Lisa M Ooms, Kellie L Tuck, Jonathan G Schoenecker, James C Whisstock, Ruby H P Law

Structure and Function Characterization of the a1a2 Motifs of Streptococcus pyogenes M Protein in Human Plasminogen Binding

化脓性链球菌M蛋白a1a2结构及在人纤溶酶原结合中的功能表征

Adam J H Quek, Blake A Mazzitelli, Guojie Wu, Eleanor W W Leung, Tom T Caradoc-Davies, Gordon J Lloyd, Devadharshini Jeevarajah, Paul J Conroy, Martina Sanderson-Smith, Yue Yuan, Yetunde A Ayinuola, Francis J Castellino, James C Whisstock, Ruby H P Law

The first transmembrane region of complement component-9 acts as a brake on its self-assembly

补体成分9的第一个跨膜区对其自组装起到抑制作用。

Bradley A Spicer ,Ruby H P Law ,Tom T Caradoc-Davies ,Sue M Ekkel ,Charles Bayly-Jones ,Siew-Siew Pang ,Paul J Conroy ,Georg Ramm ,Mazdak Radjainia ,Hariprasad Venugopal ,James C Whisstock ,Michelle A Dunstone

Inhibition of a K9/K36 demethylase by an H3.3 point mutation found in paediatric glioblastoma

在儿童胶质母细胞瘤中发现的 H3.3 点突变可抑制 K9/K36 去甲基化酶

Hsiao P J Voon, Maheshi Udugama, Wendi Lin, Linda Hii, Ruby H P Law, David L Steer, Partha P Das, Jeffrey R Mann, Lee H Wong

Structure of the poly-C9 component of the complement membrane attack complex

补体膜攻击复合物的聚-C9成分的结构

Natalya V Dudkina, Bradley A Spicer, Cyril F Reboul, Paul J Conroy, Natalya Lukoyanova, Hans Elmlund, Ruby H P Law, Susan M Ekkel, Stephanie C Kondos, Robert J A Goode, Georg Ramm, James C Whisstock, Helen R Saibil, Michelle A Dunstone

Stability of the octameric structure affects plasminogen-binding capacity of streptococcal enolase

八聚体结构的稳定性影响链球菌烯醇化酶的纤溶酶原结合能力

Amanda J Cork, Daniel J Ericsson, Ruby H P Law, Lachlan W Casey, Eugene Valkov, Carlo Bertozzi, Anna Stamp, Blagojce Jovcevski, J Andrew Aquilina, James C Whisstock, Mark J Walker, Bostjan Kobe