日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Nelarabine in T-cell acute lymphoblastic leukemia: intracellular metabolism and molecular mode-of-action

奈拉滨在T细胞急性淋巴细胞白血病中的应用：细胞内代谢和分子作用机制

期刊:Leukemia
影响因子:13.4
doi:10.1038/s41375-025-02529-2
Hormann, Femke M; Rudd, Sean G
T细胞
代谢
白血病
T细胞
细胞生物学
免疫/内分泌
发表日期：2025
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Organocatalytic Switches of DNA Glycosylase OGG1 Catalyze a Highly Efficient AP-Lyase Function

DNA糖基化酶OGG1的有机催化开关可催化高效的AP裂解酶功能

期刊:Chemistry-A European Journal
影响因子:3.7
doi:10.1002/chem.202500382
Kehler, Mario; Zhou, Kaixin; Kemas, Aurino M; Del Prado, Alicia; Hutchinson, Emma Scaletti; Nairn, Elinor Hesslefors; Varga, Marek; Plattner, Yvonne; Zhong, Yi; Purewal-Sidhu, Oryn; Haslam, James; Wiita, Elisée; Gildie, Heather; Singerova, Karolina; Szaruga, Zuzanna; Almlöf, Ingrid; Hormann, Femke M; Liu, Kang-Cheng; Wallner, Olov; Ortis, Florian; Homan, Evert J; Gileadi, Opher; Rudd, Sean G; Stenmark, Pål; de Vega, Miguel; Helleday, Thomas; D'Arcy-Evans, Nicholas D; Lauschke, Volker M; Michel, Maurice
OGG1
发表日期：2025
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Repurposing Asparaginase Therapy to Target Cisplatin-Resistant Cancer Cells.

将天冬酰胺酶疗法重新用于靶向顺铂耐药癌细胞

期刊:Fundamental & Clinical Pharmacology
影响因子:2.5
doi:10.1111/fcp.70044
Wang Jiantao, Pouryaghoub Nasim, Strauss Robert, Bartek Jiri, Zhang Si Min, Rudd Sean G
细胞生物学
肿瘤免疫
发表日期：2025
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Understanding the interplay between dNTP metabolism and genome stability in cancer

了解dNTP代谢与癌症基因组稳定性之间的相互作用

期刊:Disease Models & Mechanisms
影响因子:3.3
doi:10.1242/dmm.050775
Yagüe-Capilla, Miriam; Rudd, Sean G
肿瘤
肿瘤免疫
代谢
发表日期：2024
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Targeting pan-essential pathways in cancer with cytotoxic chemotherapy: challenges and opportunities

利用细胞毒性化疗靶向癌症中的泛必需通路：挑战与机遇

期刊:Cancer Chemotherapy and Pharmacology
影响因子:2.3
doi:10.1007/s00280-023-04562-3
Rudd, Sean G
肿瘤
肿瘤免疫
信号转导
细胞生物学
毒理研究
发表日期：2023
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Correction: Mutant p53-reactivating compound APR-246 synergizes with asparaginase in inducing growth suppression in acute lymphoblastic leukemia cells

更正：突变型p53激活化合物APR-246与天冬酰胺酶协同作用，可抑制急性淋巴细胞白血病细胞的生长。

期刊:Cell Death & Disease
影响因子:9.6
doi:10.1038/s41419-022-05130-y
Ceder, Sophia; Eriksson, Sofi E; Liang, Ying Yu; Cheteh, Emarndeena H; Zhang, Si Min; Fujihara, Kenji M; Bianchi, Julie; Bykov, Vladimir J N; Abrahmsen, Lars; Clemons, Nicholas J; Nordlund, Pär; Rudd, Sean G; Wiman, Klas G
白血病
细胞生物学
APR
发表日期：2022
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Targeting the DNA damage response and repair in cancer through nucleotide metabolism

通过核苷酸代谢靶向癌症中的DNA损伤反应和修复

期刊:Molecular Oncology
影响因子:4.5
doi:10.1002/1878-0261.13227
Helleday, Thomas; Rudd, Sean G
肿瘤
毒理研究
肿瘤免疫
代谢
发表日期：2022
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The prognostic and clinicopathological significance of desmoglein 2 in human cancers: a systematic review and meta-analysis

桥粒芯蛋白2在人类癌症中的预后和临床病理意义：系统评价和荟萃分析

期刊:PeerJ
影响因子:2.4
doi:10.7717/peerj.13141
Wang, Jiantao; Hao, Siyuan; Gu, Junjie; Rudd, Sean G; Wang, Yan
肿瘤
肿瘤免疫
发表日期：2022
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Crystal structures of NUDT15 variants enabled by a potent inhibitor reveal the structural basis for thiopurine sensitivity

利用强效抑制剂解析的NUDT15变体晶体结构揭示了硫嘌呤敏感性的结构基础。

期刊:Journal of Biological Chemistry
影响因子:3.9
doi:10.1016/j.jbc.2021.100568
Rehling, Daniel; Zhang, Si Min; Jemth, Ann-Sofie; Koolmeister, Tobias; Throup, Adam; Wallner, Olov; Scaletti, Emma; Moriyama, Takaya; Nishii, Rina; Davies, Jonathan; Desroses, Matthieu; Rudd, Sean G; Scobie, Martin; Homan, Evert; Berglund, Ulrika Warpman; Yang, Jun J; Helleday, Thomas; Stenmark, Pål
发表日期：2021
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Nucleobase and Nucleoside Analogues: Resistance and Re-Sensitisation at the Level of Pharmacokinetics, Pharmacodynamics and Metabolism

核碱基和核苷类似物：药代动力学、药效学和代谢水平上的耐药性和再致敏

期刊:Cancers
影响因子:4.4
doi:10.3390/cancers10070240
Tsesmetzis, Nikolaos; Paulin, Cynthia B J; Rudd, Sean G; Herold, Nikolas
代谢
发表日期：2018
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