日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Pharmacokinetics and pharmacodynamics of itepekimab in adults with moderate-to-severe atopic dermatitis: Results from two terminated phase II trials

伊替佩基单抗在中重度特应性皮炎成人患者中的药代动力学和药效学:两项已终止的 II 期试验的结果

Kosloski, Matthew P; Guttman-Yassky, Emma; Cork, Michael J; Worm, Margitta; Nahm, Dong-Ho; Zhu, Xiaoping; Ruddy, Marcella K; Harel, Sivan; Kamal, Mohamed A; Goulaouic, Hélène; Xu, Christine R; Avetisova, Elena; Davis, John D; Nivens, Michael C; Shabbir, Arsalan; Radin, Allen

Effect of Dupilumab on Type 2 Biomarkers in Chronic Rhinosinusitis With Nasal Polyps: SINUS-52 Study Results.

Dupilumab 对伴有鼻息肉的慢性鼻窦炎中 2 型生物标志物的影响:SINUS-52 研究结果

Bachert Claus, Laidlaw Tanya M, Cho Seong H, Mullol Joaquim, Swanson Brian N, Naimi Souad, Classe Marion, Harel Sivan, Jagerschmidt Alexandre, Laws Elizabeth, Ruddy Marcella, Praestgaard Amy, Amin Nikhil, Mannent Leda P

Efficacy and safety of dupilumab in patients with uncontrolled severe chronic rhinosinusitis with nasal polyps and a clinical diagnosis of NSAID-ERD: Results from two randomized placebo-controlled phase 3 trials

度普利尤单抗治疗伴有鼻息肉且临床诊断为非甾体抗炎药诱发呼吸道疾病(NSAID-ERD)的难治性重度慢性鼻窦炎患者的疗效和安全性:两项随机安慰剂对照3期试验的结果

Mullol, Joaquim; Laidlaw, Tanya M; Bachert, Claus; Mannent, Leda P; Canonica, G Walter; Han, Joseph K; Maspero, Jorge F; Picado, Cesar; Daizadeh, Nadia; Ortiz, Benjamin; Li, Yongtao; Ruddy, Marcella; Laws, Elizabeth; Amin, Nikhil

Preclinical and clinical experience with dupilumab on the correlates of live attenuated vaccines

dupilumab 对减毒活疫苗相关因素的临床前和临床经验

Wechsler, Michael E; Souza-Machado, Adelmir; Xu, Christine; Mao, Xuezhou; Kapoor, Upender; Khokhar, Faisal A; O'Malley, John T; Petro, Christopher D; Casullo, Veronica Mas; Mannent, Leda P; Rowe, Paul J; Jacob-Nara, Juby A; Ruddy, Marcella; Laws, Elizabeth; Purcell, Lisa A; Hardin, Megan

Understanding the key issues in the treatment of uncontrolled persistent asthma with type 2 inflammation

了解治疗伴有 2 型炎症的难治性持续性哮喘的关键问题

Busse, William W; Kraft, Monica; Rabe, Klaus F; Deniz, Yamo; Rowe, Paul J; Ruddy, Marcella; Castro, Mario

Dupilumab efficacy in adolescents with uncontrolled, moderate-to-severe asthma: LIBERTY ASTHMA QUEST

Dupilumab治疗未控制的中重度哮喘青少年患者的疗效:LIBERTY ASTHMA QUEST研究

Maspero, Jorge F; FitzGerald, John Mark; Pavord, Ian D; Rice, Megan S; Maroni, Jaman; Rowe, Paul J; Pirozzi, Gianluca; Amin, Nikhil; Ruddy, Marcella; Graham, Neil M H; Teper, Ariel; Hardin, Megan

Clinical and immunological evaluation of cat-allergic asthmatics living with or without a cat

对有猫或无猫的猫过敏性哮喘患者进行临床和免疫学评估

Wambre, Erik R; Farrington, Mary; Bajzik, Veronique; DeBerg, Hannah A; Ruddy, Marcella; DeVeaux, Michelle; Meier, Pretty; Robinson, David; Cantor, Matt; Huang, Chengrui; Orengo, Jamie M; Wang, Claire Q; Radin, Allen

Dupilumab suppresses type 2 inflammatory biomarkers across multiple atopic, allergic diseases.

Dupilumab 可抑制多种特应性过敏性疾病中的 2 型炎症生物标志物

Hamilton Jennifer D, Harel Sivan, Swanson Brian N, Brian William, Chen Zhen, Rice Megan S, Amin Nikhil, Ardeleanu Marius, Radin Allen, Shumel Brad, Ruddy Marcella, Patel Naimish, Pirozzi Gianluca, Mannent Leda, Graham Neil M H

Short-Term Subcutaneous Allergy Immunotherapy and Dupilumab are Well Tolerated in Allergic Rhinitis: A Randomized Trial

短期皮下过敏免疫疗法联合度普利尤单抗治疗过敏性鼻炎耐受性良好:一项随机试验

Corren, Jonathan; Saini, Sarbjit S; Gagnon, Remi; Moss, Mark H; Sussman, Gordon; Jacobs, Joshua; Laws, Elizabeth; Chung, Elinore S; Constant, Tatiana; Sun, Yiping; Maloney, Jennifer; Hamilton, Jennifer D; Ruddy, Marcella; Wang, Claire Q; O'Brien, Meagan P

Dupilumab Significantly Modulates Pain and Discomfort in Patients With Atopic Dermatitis: A Post Hoc Analysis of 5 Randomized Clinical Trials

度普利尤单抗显著调节特应性皮炎患者的疼痛和不适:5项随机临床试验的事后分析

Silverberg, Jonathan I; Simpson, Eric L; Guttman-Yassky, Emma; Cork, Michael J; de Bruin-Weller, Marjolein; Yosipovitch, Gil; Eckert, Laurent; Chen, Zhen; Ardeleanu, Marius; Shumel, Brad; Hultsch, Thomas; Rossi, Ana B; Hamilton, Jennifer D; Orengo, Jamie M; Ruddy, Marcella; Graham, Neil M H; Pirozzi, Gianluca; Gadkari, Abhijit