日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Overexpression of Cystine/Glutamate Antiporter xCT Correlates with Nutrient Flexibility and ZEB1 Expression in Highly Clonogenic Glioblastoma Stem-like Cells (GSCs)

胱氨酸/谷氨酸反向转运蛋白 xCT 的过度表达与高克隆形成性胶质母细胞瘤干细胞样细胞 (GSC) 中的营养灵活性和 ZEB1 表达相关

Katharina Koch, Rudolf Hartmann, Abigail Kora Suwala, Dayana Herrera Rios, Marcel Alexander Kamp, Michael Sabel, Hans-Jakob Steiger, Dieter Willbold, Amit Sharma, Ulf Dietrich Kahlert, Jarek Maciaczyk

A comparative pharmaco-metabolomic study of glutaminase inhibitors in glioma stem-like cells confirms biological effectiveness but reveals differences in target-specificity

谷氨酰胺酶抑制剂在胶质瘤干细胞中的比较药物代谢组学研究证实了其生物学有效性,但揭示了靶向特异性的差异

Katharina Koch, Rudolf Hartmann, Julia Tsiampali, Constanze Uhlmann, Ann-Christin Nickel, Xiaoling He, Marcel A Kamp, Michael Sabel, Roger A Barker, Hans-Jakob Steiger, Daniel Hänggi, Dieter Willbold, Jaroslaw Maciaczyk #, Ulf D Kahlert #

Azaphilones from the Red Sea Fungus Aspergillus falconensis

来自红海真菌 Aspergillus falconensis 的 Azaphilones

Dina H El-Kashef, Fadia S Youssef, Rudolf Hartmann, Tim-Oliver Knedel, Christoph Janiak, Wenhan Lin, Irene Reimche, Nicole Teusch, Zhen Liu, Peter Proksch

Metabolic resistance of the D-peptide RD2 developed for direct elimination of amyloid-β oligomers

开发用于直接消除淀粉样β蛋白低聚物的D肽RD2的代谢抗性

Anne Elfgen, Michelle Hupert, Kevin Bochinsky, Markus Tusche, Estibaliz González de San Román Martin, Ian Gering, Silvia Sacchi, Loredano Pollegioni, Pitter F Huesgen, Rudolf Hartmann, Beatrix Santiago-Schübel, Janine Kutzsche, Dieter Willbold

Conformational Sampling of the Intrinsically Disordered C-Terminal Tail of DERA Is Important for Enzyme Catalysis

DERA 内在无序 C 末端尾部的构象采样对酶催化至关重要

Marianne Schulte, Dušan Petrović, Philipp Neudecker, Rudolf Hartmann, Jörg Pietruszka, Sabine Willbold, Dieter Willbold, Vineet Panwalkar

New 2-Methoxy Acetylenic Acids and Pyrazole Alkaloids from the Marine Sponge Cinachyrella sp

海洋海绵Cinachyrella sp中的新2-甲氧基炔酸和吡唑生物碱

Amin Mokhlesi, Rudolf Hartmann, Tibor Kurtán, Horst Weber, Wenhan Lin, Chaidir Chaidir, Werner E G Müller, Georgios Daletos, Peter Proksch

Cyclic Cystine-Bridged Peptides from the Marine Sponge Clathria basilana Induce Apoptosis in Tumor Cells and Depolarize the Bacterial Cytoplasmic Membrane

来自海洋海绵Clathria basilana的环状胱氨酸桥肽诱导肿瘤细胞凋亡并使细菌细胞质膜去极化

Amin Mokhlesi, Fabian Stuhldreier, Katharina W Wex, Anne Berscheid, Rudolf Hartmann, Nidja Rehberg, Parichat Sureechatchaiyan, Chaidir Chaidir, Matthias U Kassack, Rainer Kalscheuer, Heike Brötz-Oesterhelt, Sebastian Wesselborg, Björn Stork, Georgios Daletos, Peter Proksch

Mechanism-based inhibition of an aldolase at high concentrations of its natural substrate acetaldehyde: structural insights and protective strategies

基于机制的醛缩酶在其天然底物乙醛高浓度下的抑制:结构见解和保护策略

Markus Dick, Rudolf Hartmann, Oliver H Weiergräber, Carolin Bisterfeld, Thomas Classen, Melanie Schwarten, Philipp Neudecker, Dieter Willbold, Jörg Pietruszka

Reciprocal regulation of the cholinic phenotype and epithelial-mesenchymal transition in glioblastoma cells

胶质母细胞瘤细胞中胆碱表型和上皮-间质转化的相互调节

Katharina Koch, Rudolf Hartmann, Friederike Schröter, Abigail Kora Suwala, Donata Maciaczyk, Andrea Caroline Krüger, Dieter Willbold, Ulf Dietrich Kahlert, Jaroslaw Maciaczyk

Structural Analysis and Aggregation Propensity of Pyroglutamate Aβ(3-40) in Aqueous Trifluoroethanol

焦谷氨酸Aβ(3-40)在三氟乙醇水溶液中的结构分析及聚集倾向

Christina Dammers, Lothar Gremer, Kerstin Reiß, Antonia N Klein, Philipp Neudecker, Rudolf Hartmann, Na Sun, Hans-Ulrich Demuth, Melanie Schwarten, Dieter Willbold