日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Rational design and in vivo validation of capsid inhibitors for enterovirus D68.

肠道病毒D68衣壳抑制剂的合理设计及体内验证。

Li Kan, Rudy Michael J, Klose Thomas, Tan Haozhou, Wu Xiangmeng, Demssie Hiwot A, Anderson Jacqueline S, Jadhav Prakash, Zhang Qing-Yu, Clarke Penny, Kuhn Richard J, Tyler Kenneth L, Wang Jun

A rationally designed 2C inhibitor prevents enterovirus D68-infected mice from developing paralysis.

合理设计的 2C 抑制剂可防止感染肠道病毒 D68 的小鼠出现瘫痪

Li Kan, Rudy Michael J, Hu Yanmei, Tan Haozhou, Lambrinidis George, Wu Xiangmeng, Georgiou Kyriakos, Tan Bin, Frost Joshua, Wilson Courtney, Clarke Penny, Kolocouris Antonios, Zhang Qing-Yu, Tyler Kenneth L, Wang Jun

EV68-228-N monoclonal antibody treatment halts progression of paralysis in a mouse model of EV-D68 induced acute flaccid myelitis.

EV68-228-N 单克隆抗体治疗可阻止 EV-D68 诱发的急性弛缓性脊髓炎小鼠模型中瘫痪的进展

Rudy Michael J, Wilson Courtney J, Hinckley Brendan, Baker Danielle C, Royal Joshua M, Hoke Marshall P, Brennan Miles B, Vogt Matthew R, Clarke Penny, Tyler Kenneth L

Neutralizing Antibody Given after Paralysis Onset Reduces the Severity of Paralysis Compared to Nonspecific Antibody-Treated Controls in a Mouse Model of EV-D68-Associated Acute Flaccid Myelitis

在EV-D68相关急性弛缓性脊髓炎小鼠模型中,与非特异性抗体治疗的对照组相比,在瘫痪发作后给予中和抗体可减轻瘫痪的严重程度。

Rudy, Michael J; Frost, Joshua; Clarke, Penny; Tyler, Kenneth L

Densities and Laminar Distributions of Kv3.1b-, PV-, GABA-, and SMI-32-Immunoreactive Neurons in Macaque Area V1

猕猴 V1 区 Kv3.1b、PV、GABA 和 SMI-32 免疫反应神经元的密度和层流分布

Jenna G Kelly, Virginia García-Marín, Bernardo Rudy, Michael J Hawken