Rueda Bo相关文献与解析，生知库 | 链接生命科学的每一步

Woo Hyun-Kyung, Philp Lauren, Jung Dae-Han, Zarrella Dominique, Chung Yein, Choi Yoonjeong, Jeon Jueun, Kim Hyunho, Castro Cesar M, Rueda Bo R, Lee Hakho

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发表日期：2026

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Normalizing the Tumor Microenvironment: A New Frontier in Ovarian Cancer Therapy

肿瘤微环境正常化：卵巢癌治疗的新前沿

期刊:International Journal of Molecular Sciences

影响因子:4.9

doi:10.3390/ijms27020939

Jones, Adam P; Zhao, Yanxia; Rueda, Bo R; Yeku, Oladapo O; Xu, Lei

Extracellular vesicles facilitate the horizontal transfer of drug resistance and stem-like properties between ovarian tumor cells

细胞外囊泡促进卵巢肿瘤细胞间耐药性和干细胞样特性的水平转移

期刊:

影响因子:

doi:10.64898/2026.01.20.699925

Pooladanda, Venkatesh; Xu, Rui; Zarrella, Dominique T; Matoba, Yusuke; Shimada, Chisa; Kumar, Shaan; Kim, Eugene; Dibenedetto, Paula; Qin, Xingping; Sarosiek, Kristopher A; Krueger, Madelyn; Magrassi, Narela; Amiji, Mansoor; Mohammadabadi, Maryam Azimi; Winter, Ursula; Castro, Cesar M; Im, Hyungsoon; Kumar, Raj; Wang, Cheng; Dahl, Karen D Cowden; Nephew, Kenneth P; Yeku, Oladapo O; Milane, Lara S; Rueda, Bo R

Hypoxia induced VEGF secretion promotes resistance to bispecific T-cell engagers.

缺氧诱导的 VEGF 分泌促进对双特异性 T 细胞衔接器的抵抗。

期刊:Signal Transduction and Targeted Therapy

影响因子:52.7

doi:10.1038/s41392-025-02505-3

Xu Mengyao, Barakzai Syem K, Kumar Raj, Veillard Irva, Kim Eugene, Bregar Amy, Eisenhauer Eric, Penson Richard, Bouberhan Sara, Filipi Jennifer, Colella Tina, Bond Tim, Clark Caroline, Lin Lawrence H, Ruan Jinpeng, Wang Cheng, Qin Xingping, Sarosiek Kristopher, Rueda Bo, Castro Cesar, Spriggs David R, Yeku Oladapo O

Extracellular vesicles modulate integrin signaling and subcellular energetics to promote pulmonary lymphangioleiomyomatosis metastasis

细胞外囊泡调节整合素信号传导和亚细胞能量代谢，从而促进肺淋巴管肌瘤病转移

期刊:Communications Biology

影响因子:5.1

doi:10.1038/s42003-025-09004-9

Kalvala, Anil Kumar; Silwal, Ashok; Patel, Bhaumik; Kasetti, Apoorva; Shetty, Kirti Rajendra; Markiewski, Jan; Cho, Jun-Hung; Lara, Gerard; Daugherity, Elizabeth; Diesler, Rémi; Pooladanda, Venkatesh; Rueda, Bo R; Henske, Elizabeth Petri; Yu, Jane J; Markiewski, Maciej; Karbowniczek, Magdalena

CCR2 improves tumor directed CAR-T cell trafficking in ovarian cancer

CCR2 可改善卵巢癌中 CAR-T 细胞向肿瘤的迁移

期刊:Frontiers in Pharmacology

影响因子:4.8

doi:10.3389/fphar.2025.1651526

Kumar, Raj; Veillard, Irva E; Xu, Mengyao; Al-Alem, Linah; Rueda, Bo R; Yeku, Oladapo O

ABL1-mediated tyrosine phosphorylation of SYCP2 contributes to transcription-coupled homologous recombination and platinum resistanceÂ in ovarian cancer.

ABL1 介导的 SYCP2 酪氨酸磷酸化促进卵巢癌的转录偶联同源重组和铂类耐药性

期刊:NAR Cancer

影响因子:3.2

doi:10.1093/narcan/zcaf031

Gao Boya, Wang Xudong, Long Melissa, Zhang Fengqi, Wang Yumin, Kumar Raj, Veillard Irva, Rueda Bo R, Yeku Oladapo, Lan Li

Paclitaxel-induced mitotic arrest results in a convergence of apoptotic dependencies that can be safely exploited by BCL-X(L) degradation to overcome cancer chemoresistance.

紫杉醇诱导的有丝分裂停滞导致细胞凋亡依赖性的趋同，而这种趋同可以通过 BCL-X(L) 降解来安全地利用，从而克服癌症的化疗耐药性

期刊:

影响因子:

doi:10.1101/2025.06.24.661170

Qin Xingping, Presser Adam, Johnson Lissah, Matoba Yusuke, Shay Brendan S, Xu Weiyi, Choiniere Jonathan, Fraser Cameron, Garbicz Filip, Spetz Johan, Yu Stacey, Florido Mary H C, Picucci Francesca, Yang Yang, Drapkin Ronny, Carrasco Ruben, Hill Sarah J, Liu Joyce, Matulonis Ursula, Brugge Joan, Rueda Bo R, Zhou Daohong, Stover Elizabeth H, Sarosiek Kristopher A

Extracellular vesicles modulate integrin signaling and subcellular energetics to promote pulmonary lymphangioleiomyomatosis metastasis.

细胞外囊泡调节整合素信号传导和亚细胞能量学，从而促进肺淋巴管肌瘤病转移

期刊:

影响因子:

doi:10.21203/rs.3.rs-5390547/v1

Karbowniczek Magdalena, Kalvala Anil, Silwal Ashok, Patel Bhaumik, Kasetti Apoorva, Shetty Kirti, Cho Jung-Hung, Lara Gerard, Daugherity Beth, Diesler Remi, Pooladanda Venkatesh, Rueda Bo, Henske Elizabeth, Yu Jane, Markiewski Maciej

Author Correction: Meiotic protein SYCP2 confers resistance to DNA-damaging agents through R-loop-mediated DNA repair

作者更正：减数分裂蛋白SYCP2通过R环介导的DNA修复赋予细胞对DNA损伤剂的抵抗力。

期刊:Nature Communications

影响因子:15.7

doi:10.1038/s41467-024-48241-0

Wang, Yumin; Gao, Boya; Zhang, Luyuan; Wang, Xudong; Zhu, Xiaolan; Yang, Haibo; Zhang, Fengqi; Zhu, Xueping; Zhou, Badi; Yao, Sean; Nagayama, Aiko; Lee, Sanghoon; Ouyang, Jian; Koh, Siang-Boon; Eisenhauer, Eric L; Zarrella, Dominique; Lu, Kate; Rueda, Bo R; Zou, Lee; Su, Xiaofeng A; Yeku, Oladapo; Ellisen, Leif W; Wang, Xiao-Song; Lan, Li

Engineering inertial flow patterns for signal amplification in disc-based protein assays.

工程化惯性流模式以在基于圆盘的蛋白质检测中实现信号放大。

Normalizing the Tumor Microenvironment: A New Frontier in Ovarian Cancer Therapy

肿瘤微环境正常化：卵巢癌治疗的新前沿

Extracellular vesicles facilitate the horizontal transfer of drug resistance and stem-like properties between ovarian tumor cells

细胞外囊泡促进卵巢肿瘤细胞间耐药性和干细胞样特性的水平转移

Hypoxia induced VEGF secretion promotes resistance to bispecific T-cell engagers.

缺氧诱导的 VEGF 分泌促进对双特异性 T 细胞衔接器的抵抗。

Extracellular vesicles modulate integrin signaling and subcellular energetics to promote pulmonary lymphangioleiomyomatosis metastasis

细胞外囊泡调节整合素信号传导和亚细胞能量代谢，从而促进肺淋巴管肌瘤病转移

CCR2 improves tumor directed CAR-T cell trafficking in ovarian cancer

CCR2 可改善卵巢癌中 CAR-T 细胞向肿瘤的迁移

ABL1-mediated tyrosine phosphorylation of SYCP2 contributes to transcription-coupled homologous recombination and platinum resistanceÂ in ovarian cancer.

ABL1 介导的 SYCP2 酪氨酸磷酸化促进卵巢癌的转录偶联同源重组和铂类耐药性

Paclitaxel-induced mitotic arrest results in a convergence of apoptotic dependencies that can be safely exploited by BCL-X(L) degradation to overcome cancer chemoresistance.

紫杉醇诱导的有丝分裂停滞导致细胞凋亡依赖性的趋同，而这种趋同可以通过 BCL-X(L) 降解来安全地利用，从而克服癌症的化疗耐药性

Extracellular vesicles modulate integrin signaling and subcellular energetics to promote pulmonary lymphangioleiomyomatosis metastasis.

细胞外囊泡调节整合素信号传导和亚细胞能量学，从而促进肺淋巴管肌瘤病转移

Author Correction: Meiotic protein SYCP2 confers resistance to DNA-damaging agents through R-loop-mediated DNA repair

作者更正：减数分裂蛋白SYCP2通过R环介导的DNA修复赋予细胞对DNA损伤剂的抵抗力。