A pooled Cell Painting CRISPR screening platform enables de novo inference of gene function by self-supervised deep learning.
一个汇集细胞涂染 CRISPR 筛选平台能够通过自监督深度学习从头推断基因功能。
期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-66778-6
Sivanandan Srinivasan, Leitmann Bobby, Lubeck Eric, Sultan Mohammad Muneeb, Stanitsas Panagiotis, Ranu Navpreet, Ewer Alexis, Mancuso Jordan E, Phillips Zachary F, Kim Albert, Bisognano John W, Cesarek John, Ruggiu Fiorella, Feldman David, Koller Daphne, Sharon Eilon, Kaykas Ajamete, Salick Max R, Chu Ci
