Andrographolide Exhibits Anticancer Activity against Breast Cancer Cells (MCF-7 and MDA-MB-231 Cells) through Suppressing Cell Proliferation and Inducing Cell Apoptosis via Inactivation of ER-α Receptor and PI3K/AKT/mTOR Signaling
穿心莲内酯通过抑制细胞增殖和诱导细胞凋亡,进而抑制ER-α受体和PI3K/AKT/mTOR信号通路,对乳腺癌细胞(MCF-7和MDA-MB-231细胞)表现出抗癌活性。
期刊:Molecules
影响因子:4.6
doi:10.3390/molecules27113544
Tohkayomatee, Ruhainee; Reabroi, Somrudee; Tungmunnithum, Duangjai; Parichatikanond, Warisara; Pinthong, Darawan
肿瘤
凋亡
表观遗传
肿瘤免疫
Apoptosis
mTOR
信号转导
乳腺癌
细胞生物学
AKT