日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Translational control of innate barrier defense by the gut microbiota

肠道菌群对先天屏障防御的翻译调控

Li, Yun; Wu, Runrun; Ma, Xianda; Zhang, Jianglin; Ma, Junjie; Duan, Yiran; Hassell, Brian; Ruhn, Kelly A; Behrendt, Cassie L; Dende, Chaitanya; Wang, Li; Lemoff, Andrew; Raj, Prithvi; Kuang, Zheng; Hooper, Lora V

The gut microbiota directs vitamin A flux to regulate intestinal T cell development.

肠道菌群引导维生素 A 的流动,从而调节肠道 T 细胞的发育。

Srinivasan Tarun, Dende Chaitanya, Ruhn Kelly A, Moye Stefanie L, Johnson Ann, Behrendt Cassie L, Hassell Brian, Vale Gonçalo, Kim Jiwoong, Lichterman Jake N, Liang Chaoying, Arana Carlos, Raj Prithvi, Zhan Xiaowei, McDonald Jeffrey G, Koh Andrew Y, Hooper Lora V

The gut microbiota reprograms intestinal lipid metabolism through long noncoding RNA Snhg9

肠道菌群通过长链非编码RNA Snhg9重编程肠道脂质代谢。

Wang, Yuhao; Wang, Meng; Chen, Jiaxin; Li, Yun; Kuang, Zheng; Dende, Chaitanya; Raj, Prithvi; Quinn, Gabriella; Hu, Zehan; Srinivasan, Tarun; Hassell, Brian; Ruhn, Kelly A; Behrendt, Cassie L; Liang, Tingbo; Dou, Xiaobing; Song, Zhangfa; Hooper, Lora V

Epithelial retinoic acid receptor β regulates serum amyloid A expression and vitamin A-dependent intestinal immunity

上皮视黄酸受体β调节血清淀粉样蛋白A表达和维生素A依赖性肠道免疫

Gattu, Sureka; Bang, Ye-Ji; Pendse, Mihir; Dende, Chaitanya; Chara, Andrew L; Harris, Tamia A; Wang, Yuhao; Ruhn, Kelly A; Kuang, Zheng; Sockanathan, Shanthini; Hooper, Lora V

Paneth cells secrete lysozyme via secretory autophagy during bacterial infection of the intestine

潘氏细胞在肠道细菌感染期间通过分泌性自噬分泌溶菌酶。

Bel, Shai; Pendse, Mihir; Wang, Yuhao; Li, Yun; Ruhn, Kelly A; Hassell, Brian; Leal, Tess; Winter, Sebastian E; Xavier, Ramnik J; Hooper, Lora V

Serum amyloid A is a retinol binding protein that transports retinol during bacterial infection

血清淀粉样蛋白A是一种视黄醇结合蛋白,在细菌感染期间运输视黄醇。

Derebe, Mehabaw G; Zlatkov, Clare M; Gattu, Sureka; Ruhn, Kelly A; Vaishnava, Shipra; Diehl, Gretchen E; MacMillan, John B; Williams, Noelle S; Hooper, Lora V

AAV-dominant negative tumor necrosis factor (DN-TNF) gene transfer to the striatum does not rescue medium spiny neurons in the YAC128 mouse model of Huntington's disease.

将 AAV 显性负性肿瘤坏死因子 (DN-TNF) 基因转移到纹状体并不能挽救亨廷顿病 YAC128 小鼠模型中的中型棘状神经元

Alto Laura Taylor, Chen Xi, Ruhn Kelly A, Treviño Isaac, Tansey Malú G

Delayed dominant-negative TNF gene therapy halts progressive loss of nigral dopaminergic neurons in a rat model of Parkinson's disease.

在帕金森病大鼠模型中,延迟显性负性 TNF 基因疗法可阻止黑质多巴胺能神经元的进行性丧失

Harms Ashley S, Barnum Christopher J, Ruhn Kelly A, Varghese Steve, Treviño Isaac, Blesch Armin, Tansey Malú G

TNF: a key neuroinflammatory mediator of neurotoxicity and neurodegeneration in models of Parkinson's disease

TNF:帕金森病模型中神经毒性和神经退行性变的关键神经炎症介质

McCoy, Melissa K; Ruhn, Kelly A; Blesch, Armin; Tansey, Malú G

Autologous transplants of Adipose-Derived Adult Stromal (ADAS) cells afford dopaminergic neuroprotection in a model of Parkinson's disease

在帕金森病模型中,自体移植脂肪来源成体基质细胞(ADAS细胞)可提供多巴胺能神经保护作用。

McCoy, Melissa K; Martinez, Terina N; Ruhn, Kelly A; Wrage, Philip C; Keefer, Edward W; Botterman, Barry R; Tansey, Keith E; Tansey, Malú G