日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

On the origin of metastases: Induction of pro-metastatic states after impending cell death via ER stress, reprogramming, and a cytokine storm

转移的起源:通过内质网应激、重编程和细胞因子风暴诱导细胞死亡后进入促转移状态

Arwen Conod, Marianna Silvano, Ariel Ruiz I Altaba

The protein secretion modulator TMED9 drives CNIH4/TGFα/GLI signaling opposing TMED3-WNT-TCF to promote colon cancer metastases

蛋白质分泌调节剂 TMED9 驱动 CNIH4/TGFα/GLI 信号传导,对抗 TMED3-WNT-TCF,促进结肠癌转移

Sonakshi Mishra, Carolina Bernal, Marianna Silvano, Santosh Anand, Ariel Ruiz I Altaba

Chimeric NANOG repressors inhibit glioblastoma growth in vivo in a context-dependent manner.

嵌合NANOG抑制因子以依赖于环境的方式在体内抑制胶质母细胞瘤的生长

Kuciak Monika, Mas Christophe, Borges Isabel, Sánchez-Gómez Pilar, Ruiz i Altaba Ariel

In vivo epigenetic reprogramming of primary human colon cancer cells enhances metastases

体内表观遗传重编程可增强原发性人结肠癌细胞的转移。

Singovski, Grigori; Bernal, Carolina; Kuciak, Monika; Siegl-Cachedenier, Irene; Conod, Arwen; Ruiz i Altaba, Ariel

Metastases and Colon Cancer Tumor Growth Display Divergent Responses to Modulation of Canonical WNT Signaling

转移瘤和结肠癌肿瘤生长对经典WNT信号通路调控表现出不同的反应

Seth, Chandan; Ruiz i Altaba, Ariel

Alberto Gulino MD, PhD (1952-2014)

阿尔贝托·古利诺医学博士、哲学博士(1952-2014)

Toftgård, R; Ruiz i Altaba, A

The river blindness drug Ivermectin and related macrocyclic lactones inhibit WNT-TCF pathway responses in human cancer

治疗河盲症的药物伊维菌素及其相关的大环内酯可抑制人类癌症中的 WNT-TCF 通路反应

Alice Melotti, Christophe Mas, Monika Kuciak, Aiala Lorente-Trigos, Isabel Borges, Ariel Ruiz i Altaba

A novel genome-wide in vivo screen for metastatic suppressors in human colon cancer identifies the positive WNT-TCF pathway modulators TMED3 and SOX12

一种新型的人类结肠癌转移抑制因子全基因组体内筛选方法,确定了 WNT-TCF 通路的正调节剂 TMED3 和 SOX12

Arnaud Duquet, Alice Melotti, Sonakshi Mishra, Monica Malerba, Chandan Seth, Arwen Conod, Ariel Ruiz i Altaba

Context-dependent signal integration by the GLI code: the oncogenic load, pathways, modifiers and implications for cancer therapy

GLI 编码的上下文依赖性信号整合:致癌负荷、通路、修饰因子及其对癌症治疗的影响

Aberger, Fritz; Ruiz i Altaba, Ariel

Loss of WNT-TCF addiction and enhancement of HH-GLI1 signalling define the metastatic transition of human colon carcinomas

WNT-TCF依赖性的丧失和HH-GLI1信号传导的增强定义了人类结肠癌的转移转变。

Varnat, Frédéric; Siegl-Cachedenier, Irene; Malerba, Monica; Gervaz, Pascal; Ruiz i Altaba, Ariel