日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Inhibition of junctional protein disruption by 2,4,6-trihydroxy-3-geranyl acetophenone in lipopolysaccharide-induced endothelial hyperpermeability via GEF-H1/RhoA/ROCK pathway.

2,4,6-三羟基-3-香叶基苯乙酮通过 GEF-H1/RhoA/ROCK 通路抑制脂多糖诱导的内皮细胞高通透性中的连接蛋白破坏。

期刊:Naunyn-Schmiedebergs Archives of Pharmacology
影响因子:3.1
doi:10.1007/s00210-025-04627-5
Chan Yee Han, Liew Kong Yen, Rullah Kamal, Harith Hanis Hazeera, Tan Ji Wei, Israf Daud Ahmad, Shaari Khozirah, Marcus Mexmollen, Tham Chau Ling
细胞生物学
内皮细胞
RHOA
ROCK
发表日期：2026
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A novel chromone-based as a potential inhibitor of ULK1 that modulates autophagy and induces apoptosis in colon cancer

一种新型色酮类化合物作为ULK1的潜在抑制剂，可调节自噬并诱导结肠癌细胞凋亡。

期刊:Future Medicinal Chemistry
影响因子:3.4
doi:10.1080/17568919.2024.2363668
Shamsudin, Nur Farisya; Leong, Sze-Wei; Koeberle, Andreas; Suriya, Utid; Rungrotmongkol, Thanyada; Chia, Suet Lin; Taher, Muhammad; Haris, Muhammad Salahuddin; Alshwyeh, Hussah Abdullah; Alosaimi, Areej A; Mediani, Ahmed; Ilowefah, Muna Abdulsalam; Islami, Deri; Mohd Faudzi, Siti Munirah; Fasihi Mohd Aluwi, Mohd Fadhlizil; Wai, Lam Kok; Rullah, Kamal
肿瘤
肠癌
表观遗传
肿瘤免疫
凋亡
ULK1
细胞生物学
自噬
发表日期：2024
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Inhibitory Effect of (2S)-Pinocembrin From Goniothalamus macrophyllus on the Prostaglandin E(2) Production in Macrophage Cell Lines: In Vitro and In Silico Studies.

来自大叶松（Goniothalamus macrophyllus）的（2S）-松柏素对巨噬细胞系中前列腺素E（2）产生的抑制作用：体外和计算机模拟研究

期刊:Advances in Pharmacological and Pharmaceutical Sciences
影响因子:3
doi:10.1155/2024/8811022
Teruna Hilwan Yuda, Rullah Kamal, Hendra Rudi, Utami Rahayu, Islami Deri, Mohd Faudzi Siti Munirah, Mohd Aluwi Mohd Fadhlizil Fasihi, Lam Kok Wai
细胞生物学
发表日期：2024
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Identification of Pyrazole Derivatives of Usnic Acid as Novel Inhibitor of SARS-CoV-2 Main Protease Through Virtual Screening Approaches

通过虚拟筛选方法鉴定出地衣酸吡唑衍生物作为SARS-CoV-2主蛋白酶的新型抑制剂

期刊:Molecular Biotechnology
影响因子:2.5
doi:10.1007/s12033-023-00667-5
Roney, Miah; Singh, Gagandeep; Huq, A K M Moyeenul; Forid, Md Shaekh; Ishak, Wan Maznah Binti Wan; Rullah, Kamal; Aluwi, Mohd Fadhlizil Fasihi Mohd; Tajuddin, Saiful Nizam
SARS-CoV-2
发表日期：2024
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Hits-to-Lead Optimization of the Natural Compound 2,4,6-Trihydroxy-3-geranyl-acetophenone (tHGA) as a Potent LOX Inhibitor: Synthesis, Structure-Activity Relationship (SAR) Study, and Computational Assignment

天然化合物2,4,6-三羟基-3-香叶基苯乙酮（tHGA）作为强效LOX抑制剂的先导化合物优化：合成、构效关系（SAR）研究和计算分配

期刊:Molecules
影响因子:4.6
doi:10.3390/molecules23102509
Ng, Chean Hui; Rullah, Kamal; Abas, Faridah; Lam, Kok Wai; Ismail, Intan Safinar; Jamaludin, Fadzureena; Shaari, Khozirah
LOX
发表日期：2018
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Synthesis and docking studies of 2,4,6-trihydroxy-3-geranylacetophenone analogs as potential lipoxygenase inhibitor

2,4,6-三羟基-3-香叶基苯乙酮类似物作为潜在脂氧合酶抑制剂的合成及分子对接研究

期刊:Molecules
影响因子:4.6
doi:10.3390/molecules190811645
Ng, Chean Hui; Rullah, Kamal; Aluwi, Mohd Fadhlizil Fasihi Mohd; Abas, Faridah; Lam, Kok Wai; Ismail, Intan Safinar; Narayanaswamy, Radhakrishnan; Jamaludin, Fadzureena; Shaari, Khozirah
发表日期：2014
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Synthesis and sar study of diarylpentanoid analogues as new anti-inflammatory agents

二芳基戊烷类化合物类似物的合成及SAR研究及其作为新型抗炎剂的潜力

期刊:Molecules
影响因子:4.6
doi:10.3390/molecules191016058
Leong, Sze Wei; Faudzi, Siti Munirah Mohd; Abas, Faridah; Aluwi, Mohd Fadhlizil Fasihi Mohd; Rullah, Kamal; Wai, Lam Kok; Bahari, Mohd Nazri Abdul; Ahmad, Syahida; Tham, Chau Ling; Shaari, Khozirah; Lajis, Nordin H
发表日期：2014
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