Rullo Anthony F相关文献与解析，生知库 | 链接生命科学的每一步

Covalent Ligand Electrophiles Are Differentially Activated by Proximity Effects Which Govern Latent Protein Reactivity

共价配体亲电试剂受邻近效应的差异性激活，而邻近效应决定了潜在的蛋白质反应活性。

期刊:ACS Central Science

影响因子:10.4

doi:10.1021/acscentsci.5c00699

Frankovich, Tomas V; McCann, Harrison M; Hoffman, Kyle S; Rullo, Anthony F

发表日期：2025

文献求助收藏

Inhibition of cell surface GRP78 and activated Î±2M interaction attenuates kidney fibrosis.

抑制细胞表面 GRP78 和活化的 α2M 相互作用可减轻肾纤维化。

期刊:JCI Insight

影响因子:6.1

doi:10.1172/jci.insight.183998

Trink Jackie, Nmecha Ifeanyi Kennedy, Pilely Katrine, Li Renzhong, Yang Zi, Kwiecien Sydney, MacDonald Melissa, Gao Bo, Mamai Mariam A, Lu Chao, Bajwa Urooj F, Uppal Nikhil, Fredenburgh James C, Kakoki Masao, Pizzo Salvatore V, Rullo Anthony F, Lanktree Matthew B, Weitz Jeffrey I, Palarasah Yaseelan, Krepinsky Joan C

细胞生物学

发表日期：2025

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Offsetting Low-Affinity Carbohydrate Binding with Covalency to Engage Sugar-Specific Proteins for Tumor-Immune Proximity Induction

利用共价键抵消低亲和力碳水化合物结合，从而激活糖特异性蛋白，诱导肿瘤免疫邻近效应

期刊:ACS Central Science

影响因子:10.4

doi:10.1021/acscentsci.3c01052

Lake, Benjamin P M; Rullo, Anthony F

Orchestrating Binding Interactions and the Emergence of Avidity Driven Therapeutics

调控结合相互作用与亲和力驱动疗法的出现

期刊:ACS Central Science

影响因子:10.4

doi:10.1021/acscentsci.3c00242

Kapcan, Eden; Lake, Benjamin P M; Rullo, Anthony F

信号转导

发表日期：2023

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A covalent opsonization approach to enhance synthetic immunity against viral escape variants

利用共价调理作用增强针对病毒逃逸变异株的合成免疫力

期刊:Cell Reports Physical Science

影响因子:7.3

doi:10.1016/j.xcrp.2023.101258

Kapcan, Eden; Rullo, Anthony F

Re-engineering the Immune Response to Metastatic Cancer: Antibody-Recruiting Small Molecules Targeting the Urokinase Receptor

重塑针对转移性癌症的免疫反应：靶向尿激酶受体的抗体募集小分子

期刊:Angewandte Chemie-International Edition

影响因子:16.9

doi:10.1002/anie.201510866

Rullo, Anthony F; Fitzgerald, Kelly J; Muthusamy, Viswanathan; Liu, Min; Yuan, Cai; Huang, Mingdong; Kim, Minsup; Cho, Art E; Spiegel, David A

Mimicry of molecular glues using dual covalent chimeras.

利用双共价嵌合体模拟分子胶

Covalent Ligand Electrophiles Are Differentially Activated by Proximity Effects Which Govern Latent Protein Reactivity

共价配体亲电试剂受邻近效应的差异性激活，而邻近效应决定了潜在的蛋白质反应活性。

Inhibition of cell surface GRP78 and activated Î±2M interaction attenuates kidney fibrosis.

抑制细胞表面 GRP78 和活化的 α2M 相互作用可减轻肾纤维化。

Offsetting Low-Affinity Carbohydrate Binding with Covalency to Engage Sugar-Specific Proteins for Tumor-Immune Proximity Induction

利用共价键抵消低亲和力碳水化合物结合，从而激活糖特异性蛋白，诱导肿瘤免疫邻近效应

Orchestrating Binding Interactions and the Emergence of Avidity Driven Therapeutics

调控结合相互作用与亲和力驱动疗法的出现

A covalent opsonization approach to enhance synthetic immunity against viral escape variants

利用共价调理作用增强针对病毒逃逸变异株的合成免疫力

Re-engineering the Immune Response to Metastatic Cancer: Antibody-Recruiting Small Molecules Targeting the Urokinase Receptor

重塑针对转移性癌症的免疫反应：靶向尿激酶受体的抗体募集小分子