日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The RNA exosome maintains cellular RNA homeostasis by controlling transcript abundance in the brain

RNA外泌体通过控制大脑中的转录本丰度来维持细胞RNA稳态。

Lauryn A Higginson,Xingjun Wang,Kevin He,Maggie Torstrick,Minhoo Kim,H R Sagara Wijeratne,Avery M Runnebohm,Bérénice A Benayoun,Adam MacLean,Guillaume F Chanfreau,Derrick J Morton

EXOSC3 G191 Variants Trigger System-Wide Recalibration of RNA Processing Machinery

EXOSC3 G191 变异体触发 RNA 加工机制的系统性重新校准

Wijeratne, H R Sagara; Runnebohm, Avery M; Barron, Monica P; Hampton, Ariana J; Li, Rudong; Peck Justice, Sarah A; Lenceski, Sophia H; Rooney, James D; Smith-Kinnaman, Whitney R; Chang, Gina S; Doud, Emma H; Kim, Jungsu; Pelletier, Stephane; Liu, Yunlong; Vilseck, Jonah Z; Mosley, Amber L

Quantifying the Structural and Energetic Consequences of EXOSC3 S1 Domain Variants from a Comparative Assessment of λ-Dynamics with Two Charge-Changing Perturbation Strategies

通过两种电荷改变扰动策略对λ动力学的比较评估,量化EXOSC3 S1结构域变体的结构和能量后果

Barron, Monica P; Wijeratne, H R Sagara; Runnebohm, Avery M; Caric, Katelyn M; Mosley, Amber L; Vilseck, Jonah Z

EXOSC3 S1-domain variants implicated in PCH1b alter RNA exosome cap subunit abundance and thermal stability disrupting rRNA processing and targeting of AU-rich mRNA.

与 PCH1b 相关的 EXOSC3 S1 结构域变体改变了 RNA 外泌体帽亚基的丰度和热稳定性,从而破坏了 rRNA 加工和富含 AU 的 mRNA 的靶向

Runnebohm Avery M, Wijeratne H R Sagara, Barron Monica P, Smith-Kinnaman Whitney R, Rooney James D, Peck Justice Sarah A, Cureton Lauryn A, Holland Annalise, Ghalei Homa, Pelletier Stephane, Doud Emma H, Vilseck Jonah Z, Mosley Amber L

IB-DNQ and Rucaparib dual treatment alters cell cycle regulation and DNA repair in triple negative breast cancer cells

IB-DNQ 和 Rucaparib 双重治疗改变三阴性乳腺癌细胞的细胞周期调控和 DNA 修复

Avery M Runnebohm, H R Sagara Wijeratne, Sarah A Peck Justice, Aruna B Wijeratne, Gitanjali Roy, Naveen Singh, Paul Hergenrother, David A Boothman, Edward A Motea, Amber L Mosley

Obtaining Functional Proteomics Insights From Thermal Proteome Profiling Through Optimized Melt Shift Calculation and Statistical Analysis With InflectSSP

通过使用 InflectSSP 优化熔解位移计算和统计分析,从热蛋白质组分析中获取功能蛋白质组学见解

Neil A McCracken, Hao Liu, Avery M Runnebohm, H R Sagara Wijeratne, Aruna B Wijeratne, Kirk A Staschke, Amber L Mosley

Methionine Restriction Impairs Degradation of a Protein that Aberrantly Engages the Endoplasmic Reticulum Translocon

甲硫氨酸限制会损害一种异常结合内质网转位子的蛋白质的降解。

Runnebohm, Avery M; Indovina, Christopher J; Turk, Samantha M; Bailey, Connor G; Orchard, Cade J; Wade, Lauren; Overton, Danielle L; Snow, Brian J; Rubenstein, Eric M

Overlapping function of Hrd1 and Ste24 in translocon quality control provides robust channel surveillance

Hrd1 和 Ste24 在转位子质量控制中的重叠功能提供了强大的通道监测能力

Runnebohm, Avery M; Richards, Kyle A; Irelan, Courtney Broshar; Turk, Samantha M; Vitali, Halie E; Indovina, Christopher J; Rubenstein, Eric M