日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Vaccination of mice with Trichinella spiralis serine proteinase enhanced gut epithelial barrier and elicited a high protective immunity

用旋毛虫丝氨酸蛋白酶对小鼠进行免疫接种可增强肠道上皮屏障功能并诱导产生高度保护性免疫力。

期刊:PLoS Neglected Tropical Diseases
影响因子:3.4
doi:10.1371/journal.pntd.0014161
Wu, Jin Yi; Zhang, Xin Zhuo; Zhang, Ru; Zhang, Yao; Liu, Ruo Dan; Zhang, Xi; Long, Shao Rong; Wang, Zhong Quan; Cui, Jing
免疫/内分泌
发表日期：2026
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Trichinella spiralis serine proteinase enhances antibody-dependent cell-mediated (ADCC) killing of newborn larvae by driving M1 polarization via the NF-κB pathway

旋毛虫丝氨酸蛋白酶通过NF-κB通路驱动M1极化，从而增强抗体依赖性细胞介导的（ADCC）对新生幼虫的杀伤作用。

期刊:Parasite
影响因子:2.4
doi:10.1051/parasite/2026020
Wu, Jin Yi; Zhang, Ru; Zhang, Yao; Zhang, Xin Zhuo; Xu, Dong Mei; Liu, Ruo Dan; Long, Shao Rong; Wang, Zhong Quan; Cui, Jing
NF-κB
信号转导
细胞生物学
DCC
发表日期：2026
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Late steps of allelic break-induced replication suppress tandem duplication associated with BRCA1 deficiency.

等位基因断裂诱导复制的后期步骤抑制与 BRCA1 缺陷相关的串联重复

期刊:Nucleic Acids Research
影响因子:13.1
doi:10.1093/nar/gkaf729
Huang Zhi-Cheng, Feng Yi-Li, Liu Qian, Chen Ruo-Dan, Liu Si-Cheng, Wang Meng, Xie An-Yong
其它
发表日期：2025
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Post-cleavage target residence determines asymmetry in non-homologous end joining of Cas12a-induced DNA double strand breaks.

切割后靶标停留决定了 Cas12a 诱导的 DNA 双链断裂非同源末端连接的不对称性

期刊:Genome Biology
影响因子:9.4
doi:10.1186/s13059-025-03567-w
Chen Ruo-Dan, Yang Yi, Liu Kun-Ming, Hu Jing-Zhen, Feng Yi-Li, Yang Chun-Yi, Jiang Rui-Rui, Liu Si-Cheng, Wang Yue, Han Ping-An, Tian Ru-Gang, Wang Yu-Long, Xu Shi-Ming, Xie An-Yong
其它
发表日期：2025
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Aspartic protease 2 from Trichinella spiralis excretion/secretion products hydrolyzes tight junctions of intestinal epithelial cells

旋毛虫排泄/分泌产物中的天冬氨酸蛋白酶2可水解肠上皮细胞的紧密连接。

期刊:PLoS Neglected Tropical Diseases
影响因子:3.4
doi:10.1371/journal.pntd.0013805
Long, Shao Rong; Zhang, Hui Ran; Wang, Jing Jing; Liao, Zi Xuan; Fan, Qi Xue; Liang, Yu Qing; Gan, Cheng Yu; Liu, Ruo Dan; Cui, Jing; Zhang, Xi; Wang, Zhong Quan; Qi, Xin
上皮细胞
细胞生物学
发表日期：2025
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Vaccination of mice with Trichinella spiralis C-type lectin elicited the protective immunity and enhanced gut epithelial barrier function

用旋毛虫C型凝集素对小鼠进行免疫接种，可诱导保护性免疫并增强肠道上皮屏障功能。

期刊:PLoS Neglected Tropical Diseases
影响因子:3.4
doi:10.1371/journal.pntd.0012825
Wang, Bo Ning; Zhang, Xin Zhuo; Wu, Jin Yi; Zhang, Zhao Yu; Cong, Pei Kun; Zheng, Wen Wen; Long, Shao Rong; Liu, Ruo Dan; Cui, Jing; Wang, Zhong Quan
免疫/内分泌
发表日期：2025
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Trichinella spiralis excretory-secretory proteins induced autophagy via activating AMPK/mTOR pathway and protected gut epithelial barrier

旋毛虫排泄分泌蛋白通过激活AMPK/mTOR通路诱导自噬，并保护肠道上皮屏障。

期刊:PLoS Neglected Tropical Diseases
影响因子:3.4
doi:10.1371/journal.pntd.0013863
Zhang, Xin Zhuo; Zhang, Yao; Zhang, Ru; Wu, Jin Yi; Cong, Pei Kun; Long, Shao Rong; Liu, Ruo Dan; Wang, Zhong Quan; Cui, Jing
信号转导
AMPK
mTOR
自噬
发表日期：2025
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A Trichinella spiralis serine protease triggers gut epithelial apoptosis and destroys the barrier integrity to mediate larval invasion

旋毛虫丝氨酸蛋白酶可诱导肠道上皮细胞凋亡并破坏肠道屏障完整性，从而促进幼虫入侵。

期刊:PLoS Neglected Tropical Diseases
影响因子:3.4
doi:10.1371/journal.pntd.0013680
Lu, Qi Qi; Zhang, Xin Zhuo; Cong, Pei Kun; Wu, Jin Yi; Gao, Tian Ran; Long, Shao Rong; Liu, Ruo Dan; Wang, Zhong Quan; Cui, Jing
上皮细胞
细胞生物学
凋亡
表观遗传
发表日期：2025
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Trichinella spiralis serine protease mediates larval invasion of gut epithelium via binding to CK8 and activating RhoA/ROCK1 pathway.

旋毛虫丝氨酸蛋白酶通过与 CK8 结合并激活 RhoA/ROCK1 通路来介导幼虫入侵肠道上皮。

期刊:PLoS Neglected Tropical Diseases
影响因子:3.4
doi:10.1371/journal.pntd.0013725
Zheng Wen Wen, Zhang Xin Zhuo, Cong Pei Kun, Zhang Ru, Long Shao Rong, Zhang Xi, Liu Ruo Dan, Wang Zhong Quan, Cui Jing
信号转导
RHOA
ROCK
ROCK1
发表日期：2025
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Biological characteristics of a new long-chain fatty acid transport protein 1 from Trichinella spiralis and its participation in lipid metabolism, larval moulting, and development

旋毛虫新长链脂肪酸转运蛋白1的生物学特性及其参与脂质代谢、幼虫蜕皮和发育

期刊:Veterinary Research
影响因子:3.7
doi:10.1186/s13567-024-01380-0
Yang Li Li, Qi Qi Lu, Wen Wen Zheng, Zhao Yu Zhang, Jin Yi Wu, Mei Hao Wei, Xin Zhuo Zhang, Ruo Dan Liu, Zhong Quan Wang, Jing Cui
代谢
发表日期：2024
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