日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

The high efficacy of claudin18.2-targeted CAR-T cell therapy in advanced pancreatic cancer with an antibody-dependent safety strategy

针对 Claudin18.2 的 CAR-T 细胞疗法在晚期胰腺癌中具有高效性，且采用抗体依赖性安全策略

期刊:Molecular Therapy
影响因子:12.1
doi:10.1016/j.ymthe.2025.01.012
Guocheng Zhong ，Xiaomin Zhang ，Ruocong Zhao ，Zheng Guo ，Chenguang Wang ，Chuan Yu ，Dongzhe Liu ，Ke Hu ，Yujie Gao ，Bochen Zhao ，Xianhao Liu ，Xuanren Shi ，Lei Chen ，Yisheng Li ，Li Yu
肿瘤
胰腺癌
发表日期：2025
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Co-expression of a PD-L1-specific chimeric switch receptor augments the efficacy and persistence of CAR T cells via the CD70-CD27 axis

PD-L1特异性嵌合开关受体的共表达可通过CD70-CD27轴增强CAR T细胞的疗效和持久性。

期刊:Nature Communications
影响因子:14.7
doi:10.1038/s41467-022-33793-w
Le Qin ，Yuanbin Cui ，Tingjie Yuan ，Dongmei Chen ，Ruocong Zhao ，Shanglin Li ，Zhiwu Jiang ，Qiting Wu ，Youguo Long ，Suna Wang ，Zhaoyang Tang ，Huixia Pan ，Xiaoping Li ，Wei Wei ，Jie Yang ，Xuequn Luo ，Zhenfeng Zhang ，Qiannan Tang ，Pentao Liu ，Robert Weinkove ，Yao Yao ，Dajiang Qin ，Jean Paul Thiery ，Peng Li
T细胞
信号转导
免疫/内分泌
PD-L1
CD2
CD7
细胞生物学
CD27
CD70
T细胞
发表日期：2022
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BET bromodomain inhibition rescues PD-1-mediated T-cell exhaustion in acute myeloid leukemia

BET溴结构域抑制剂可挽救急性髓系白血病中PD-1介导的T细胞耗竭

期刊:Cell Death & Disease
影响因子:8.1
doi:10.1038/s41419-022-05123-x
Mengjun Zhong # ，Rili Gao # ，Ruocong Zhao # ，Youxue Huang ，Cunte Chen ，Kehan Li ，Xibao Yu ，Dingrui Nie ，Zheng Chen ，Xin Liu ，Zhuandi Liu ，Shaohua Chen ，Yuhong Lu ，Zhi Yu ，Liang Wang ，Peng Li ，Chengwu Zeng ，Yangqiu Li
T细胞
免疫/内分泌
细胞生物学
PD-1
白血病
T细胞
发表日期：2022
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The Chemokine Receptor CCR8 Is a Target of Chimeric Antigen T Cells for Treating T Cell Malignancies

趋化因子受体CCR8是嵌合抗原T细胞治疗T细胞恶性肿瘤的靶点。

期刊:Frontiers in Immunology
影响因子:5.7
doi:10.3389/fimmu.2022.808347
Diwei Zheng ，Xindong Wang ，Lin Cheng ，Le Qin ，Zhiwu Jiang ，Ruocong Zhao ，Yao Li ，Jingxuan Shi ，Qiting Wu ，Youguo Long ，Suna Wang ，Zhaoyang Tang ，Wei Wei ，Jie Yang ，Yangqiu Li ，Hongsheng Zhou ，Qifa Liu ，Pentao Liu ，Xinwen Chen ，Yao Yao ，LiHua Yang ，Peng Li
细胞生物学
免疫/内分泌
肿瘤免疫
肿瘤
T细胞
T细胞
信号转导
CCR8
发表日期：2022
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DAP10 integration in CAR-T cells enhances the killing of heterogeneous tumors by harnessing endogenous NKG2D

DAP10 整合到 CAR-T 细胞中，通过利用内源性 NKG2D 增强对异质性肿瘤的杀伤

期刊:Molecular Therapy-Oncolytics
影响因子:5.3
doi:10.1016/j.omto.2022.06.003
Shanglin Li, Ruocong Zhao, Diwei Zheng, Le Qin, Yuanbin Cui, Yao Li, Zhiwu Jiang, Mengjun Zhong, Jingxuan Shi, Ming Li, Xindong Wang, Zhaoyang Tang, Qiting Wu, Youguo Long, Duo Hu, Suna Wang, Yao Yao, Shuang Liu, Li-Hua Yang, Zhenfeng Zhang, Qiannan Tang, Pentao Liu, Yangqiu Li, Peng Li
肿瘤
T细胞
发表日期：2022
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Disruption of CISH promotes the antitumor activity of human T cells and decreases PD-1 expression levels

CISH 的破坏促进了人类 T 细胞的抗肿瘤活性并降低了 PD-1 表达水平

期刊:Molecular Therapy-Oncolytics
影响因子:5.3
doi:10.1016/j.omto.2022.12.003
Jiang Lv, Le Qin, Ruocong Zhao, Di Wu, Zhiping Wu, Diwei Zheng, Siyu Li, Mintao Luo, Qiting Wu, Youguo Long, Zhaoyang Tang, Yan-Lai Tang, Xuequn Luo, Yao Yao, Li-Hua Yang, Peng Li
肿瘤
T细胞
发表日期：2022
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Human Hyaluronidase PH20 Potentiates the Antitumor Activities of Mesothelin-Specific CAR-T Cells Against Gastric Cancer

人透明质酸酶 PH20 增强间皮素特异性 CAR-T 细胞对胃癌的抗肿瘤活性

期刊:Frontiers in Immunology
影响因子:5.7
doi:10.3389/fimmu.2021.660488
Ruocong Zhao, Yuanbin Cui, Yongfang Zheng, Shanglin Li, Jiang Lv, Qiting Wu, Youguo Long, Suna Wang, Yao Yao, Wei Wei, Jie Yang, Bin-Chao Wang, Zhenfeng Zhang, Hui Zeng, Yangqiu Li, Peng Li
肿瘤
胃癌
肿瘤细胞
发表日期：2021
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Chimeric antigen receptor T cells targeting PD-L1 suppress tumor growth

针对 PD-L1 的嵌合抗原受体 T 细胞抑制肿瘤生长

期刊:Biomarker Research
影响因子:9.5
doi:10.1186/s40364-020-00198-0
Le Qin, Ruocong Zhao, Dongmei Chen, Xinru Wei, Qiting Wu, Youguo Long, Zhiwu Jiang, Yangqiu Li, Haipeng Wu, Xuchao Zhang, Yilong Wu, Shuzhong Cui, Wei Wei, Huihui Yao, Zixia Liu, Su Cao, Yao Yao, Zhenfeng Zhang, Peng Li
肿瘤
T细胞
发表日期：2020
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PSCA is a target of chimeric antigen receptor T cells in gastric cancer

PSCA 是胃癌中嵌合抗原受体 T 细胞的靶点

期刊:Biomarker Research
影响因子:9.5
doi:10.1186/s40364-020-0183-x
Di Wu, Jiang Lv, Ruocong Zhao, Zhiping Wu, Diwei Zheng, Jingxuan Shi, Simiao Lin, Suna Wang, Qiting Wu, Youguo Long, Peng Li, Yao Yao
肿瘤
胃癌
T细胞
发表日期：2020
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Mesothelin is a target of chimeric antigen receptor T cells for treating gastric cancer

间皮素是治疗胃癌的嵌合抗原受体 T 细胞的靶点

期刊:Journal of Hematology & Oncology
影响因子:29.5
doi:10.1186/s13045-019-0704-y
Jiang Lv, Ruocong Zhao, Di Wu, Diwei Zheng, Zhiping Wu, Jingxuan Shi, Xinru Wei, Qiting Wu, Youguo Long, Simiao Lin, Suna Wang, Zhi Wang, Yang Li, Yantao Chen, Qing He, Suimin Chen, Huihui Yao, Zixia Liu, Zhaoyang Tang, Yao Yao, Duanqing Pei, Pentao Liu, Xuchao Zhang, Zhenfeng Zhang, Shuzhong Cui, R
免疫
细胞生物学
胃癌
肿瘤细胞
T Cell Receptor
发表日期：2019
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