日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Targeting the angiopoietin-like protein 3/8 complex with a monoclonal antibody in patients with mixed hyperlipidemia: a phase 1 trial

使用单克隆抗体靶向血管生成素样蛋白3/8复合物治疗混合型高脂血症患者：一项I期试验

期刊:Nature Medicine
影响因子:50
doi:10.1038/s41591-025-03830-4
Gaudet, Daniel; Gonciarz, Malgorzata; Shen, Xi; Leohr, Jennifer K; Beyer, Thomas P; Day, Jonathan W; Mullins, Garrett R; Zhen, Eugene Y; Hartley, Maryalice; Larouche, Miriam; Konrad, Robert J; Benichou, Olivier; Ruotolo, Giacomo
单克隆抗体
血管生成
发表日期：2025
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Decreases in circulating ANGPTL3/8 concentrations following retatrutide treatment parallel reductions in serum lipids

瑞他曲肽治疗后循环 ANGPTL3/8 浓度的降低与血脂的降低平行。

期刊:Diabetes Obesity & Metabolism
影响因子:5.7
doi:10.1111/dom.16661
Wen, Yi; Lemen, Deven; Lin, Yanzhu; Chen, Yan Q; Regmi, Ajit; Roell, William C; Thomas, Melissa K; Hartman, Mark L; Coskun, Tamer; Milicevic, Zvonko; Haupt, Axel; Ruotolo, Giacomo; Konrad, Robert J
发表日期：2025
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Pharmacological Inhibition of CETP (Cholesteryl Ester Transfer Protein) Increases HDL (High-Density Lipoprotein) That Contains ApoC3 and Other HDL Subspecies Associated With Higher Risk of Coronary Heart Disease

胆固醇酯转移蛋白 (CETP) 的药理学抑制可增加含有载脂蛋白 C3 (ApoC3) 和其他与冠心病风险增加相关的 HDL 亚型的 HDL（高密度脂蛋白）。

期刊:Arteriosclerosis Thrombosis and Vascular Biology
影响因子:7.4
doi:10.1161/ATVBAHA.121.317181
Furtado, Jeremy D; Ruotolo, Giacomo; Nicholls, Stephen J; Dullea, Robert; Carvajal-Gonzalez, Santos; Sacks, Frank M
代谢
心血管
冠心病
发表日期：2022
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The dual glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 receptor agonist tirzepatide improves cardiovascular risk biomarkers in patients with type 2 diabetes: A post hoc analysis.

双重葡萄糖依赖性促胰岛素多肽和胰高血糖素样肽-1受体激动剂替拉帕肽可改善2型糖尿病患者的心血管风险生物标志物：一项事后分析

期刊:Diabetes Obesity & Metabolism
影响因子:5.7
doi:10.1111/dom.14553
Wilson Jonathan M, Lin Yanzhu, Luo M Jane, Considine Gary, Cox Amy L, Bowsman Lenden M, Robins Deborah A, Haupt Axel, Duffin Kevin L, Ruotolo Giacomo
心血管
糖尿病
血管生成
发表日期：2022
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Effect of C-Reactive Protein on Lipoprotein(a)-Associated Cardiovascular Risk in Optimally Treated Patients With High-Risk Vascular Disease: A Prespecified Secondary Analysis of the ACCELERATE Trial

C反应蛋白对接受最佳治疗的高危血管疾病患者脂蛋白(a)相关心血管风险的影响：ACCELERATE试验的预设二次分析

期刊:Jama Cardiology
影响因子:14.1
doi:10.1001/jamacardio.2020.2413
Puri, Rishi; Nissen, Steven E; Arsenault, Benoit J; St John, Julie; Riesmeyer, Jeffrey S; Ruotolo, Giacomo; McErlean, Ellen; Menon, Venu; Cho, Leslie; Wolski, Kathy; Lincoff, A Michael; Nicholls, Stephen J
CEL
发表日期：2020
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The dual glucose-dependent insulinotropic peptide and glucagon-like peptide-1 receptor agonist, tirzepatide, improves lipoprotein biomarkers associated with insulin resistance and cardiovascular risk in patients with type 2 diabetes

替泽帕肽是一种双重葡萄糖依赖性促胰岛素肽和胰高血糖素样肽-1受体激动剂，可改善2型糖尿病患者与胰岛素抵抗和心血管风险相关的脂蛋白生物标志物。

期刊:Diabetes Obesity & Metabolism
影响因子:5.7
doi:10.1111/dom.14174
Wilson, Jonathan M; Nikooienejad, Amir; Robins, Deborah A; Roell, William C; Riesmeyer, Jeffrey S; Haupt, Axel; Duffin, Kevin L; Taskinen, Marja-Riitta; Ruotolo, Giacomo
代谢
糖尿病
信号转导
免疫/内分泌
发表日期：2020
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Impact of Baseline Glycemic Control on Residual Cardiovascular Risk in Patients With Diabetes Mellitus and High-Risk Vascular Disease Treated With Statin Therapy

基线血糖控制对接受他汀类药物治疗的糖尿病合并高危血管疾病患者残余心血管风险的影响

期刊:Journal of the American Heart Association
影响因子:5.3
doi:10.1161/JAHA.119.014328
Menon, Venu; Kumar, Anirudh; Patel, Divyang R; John, Julie St; Wolski, Kathy E; McErlean, Ellen; Riesmeyer, Jeffrey S; Weerakkody, Govinda; Ruotolo, Giacomo; Cremer, Paul C; Nicholls, Stephen J; Lincoff, A Michael; Nissen, Steven E
糖尿病
代谢
发表日期：2020
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Effect of CETP inhibition with evacetrapib in patients with diabetes mellitus enrolled in the ACCELERATE trial

在 ACCELERATE 试验中，依伐西曲匹（evacetrapib）作为 CETP 抑制剂对糖尿病患者的影响

期刊:Bmj Open Diabetes Research & Care
影响因子:4.1
doi:10.1136/bmjdrc-2019-000943
Menon, Venu; Kumar, Anirudh; Patel, Divyang R; St John, Julie; Riesmeyer, Jeffrey; Weerakkody, Govinda; Ruotolo, Giacomo; Wolski, Kathy E; McErlean, Ellen; Cremer, Paul C; Nicholls, Stephen J; Lincoff, A Michael; Nissen, Steven E
CEL
糖尿病
代谢
发表日期：2020
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Proceedings of the Ninth HDL (High-Density Lipoprotein) Workshop: Focus on Cardiovascular Disease

第九届高密度脂蛋白（HDL）研讨会论文集：聚焦心血管疾病

期刊:Arteriosclerosis Thrombosis and Vascular Biology
影响因子:7.4
doi:10.1161/ATVBAHA.119.313340
Rodriguez, Annabelle; Trigatti, Bernardo L; Mineo, Chieko; Knaack, Darcy; Wilkins, John T; Sahoo, Daisy; Asztalos, Bela F; Mora, Samia; Cuchel, Marina; Pownall, Henry J; Rosales, Corina; Bernatchez, Pascal; Ribeiro Martins da Silva, Amanda; Getz, Godfrey S; Barber, Jacob L; Shearer, Gregory C; Zivkovic, Angela M; Tietge, Uwe J F; Sacks, Frank M; Connelly, Margery A; Oda, Michael N; Davidson, W Sean; Sorci-Thomas, Mary G; Vaisar, Tomas; Ruotolo, Giacomo; Vickers, Kasey C; Martel, Catherine
心血管疾病
心血管
发表日期：2019
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Plasma Aldosterone Levels Are Not Associated With Cardiovascular Events Among Patients With High-Risk Vascular Disease: Insights From the ACCELERATE Trial

血浆醛固酮水平与高危血管疾病患者的心血管事件无关：来自 ACCELERATE 试验的启示

期刊:Journal of the American Heart Association
影响因子:5.3
doi:10.1161/JAHA.119.013790
Kumar, Anirudh; Patel, Divyang R; Brennan, Danielle M; Wolski, Kathy E; Lincoff, A Michael; Ruotolo, Giacomo; McErlean, Ellen; Weerakkody, Govinda; Riesmeyer, Jeffrey S; Nicholls, Stephen J; Nissen, Steven E; Menon, Venu
CEL
发表日期：2019
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