Pre-existing anti-polyethylene glycol antibody linked to first-exposure allergic reactions to pegnivacogin, a PEGylated RNA aptamer
预先存在的抗聚乙二醇抗体与首次接触聚乙二醇化RNA适体pegnivacogin的过敏反应有关
期刊:Journal of Allergy and Clinical Immunology
影响因子:11.2
doi:10.1016/j.jaci.2015.10.034
Ganson, Nancy J; Povsic, Thomas J; Sullenger, Bruce A; Alexander, John H; Zelenkofske, Steven L; Sailstad, Jeffrey M; Rusconi, Christopher P; Hershfield, Michael S