Triple checkpoint blockade of PD-1, Tim-3, and Lag-3 enhances adoptive T cell immunotherapy in a mouse model of ovarian cancer
在卵巢癌小鼠模型中,PD-1、Tim-3 和 Lag-3 三重检查点阻断可增强过继性 T 细胞免疫疗法的疗效。
期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2419888122
Alencar, Gabriel F; Mohamed, Asmaa O; Burnett, Madison G; Jean, Samantha St; Nelson, Anders R; Su, Yapeng; Voillet, Valentin; Bates, Breanna M; Rodgers Suarez, Magdalia; Ruskin, Susan L; Trieu, Lam; Lam, Jennifer L; Bekiranov, Stefan; Gottardo, Raphael; Greenberg, Philip D; Anderson, Kristin G
肿瘤
T细胞
肿瘤免疫
卵巢癌
细胞生物学
PD-1
免疫/内分泌