Leveraging glucan-induced trained immunity for the epigenetic and metabolic rewiring of macrophages to enhance colorectal cancer vaccine response.
利用葡聚糖诱导的训练免疫对巨噬细胞进行表观遗传和代谢重编程，以增强结直肠癌疫苗反应。
期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-026-68466-5
Hamdan Firas, Gandolfi Sara, D'Alessio Federica, Giannoula Yvonne, Kolikova Julia, Fusciello Manlio, Zaghen Elisa, Napolano Alessandra, Russo Salvatore, Izci Ozan, Bottega Paolo, Chiaro Jacopo, Alanen Kirsi-Marja, Antignani Gabriella, Feodoroff Michaela, Stigzelius Virpi, Sakalauskaite Milda, Sandberg Janita, Nieminen Anni I, Zambrano Nicola, Eriksson Ove, Mustjoki Satu, Seppälä Toni T, Grönholm Mikaela, Cerullo Vincenzo
巨噬细胞
肿瘤
肠癌
表观遗传
肿瘤免疫
巨噬细胞
代谢
代谢重编程
细胞生物学
免疫/内分泌
