日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Phase I Clinical Trial of High Doses of Seleno-L-methionine in Combination with Axitinib in Patients with Previously Treated Metastatic Clear-cell Renal Cell Carcinoma.

高剂量硒代-L-蛋氨酸联合阿昔替尼治疗既往接受过治疗的转移性透明细胞肾细胞癌患者的 I 期临床试验

期刊:Clinical Cancer Research
影响因子:10.2
doi:10.1158/1078-0432.CCR-24-3234
Zakharia Yousef, Reis Ryan J, Kroll Matthew R, Rataan Aseel O, Manchkanti Srija, Rahim Bilal, Garje Rohan, Swami Umang, Mott Sarah L, Zamba K D, Sieren Jessica C, Salem Aliasger K, Rustum Youcef
细胞生物学
发表日期：2025
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Targeting transforming growth factor-β1 by methylseleninic acid/seleno-L-methionine in clear cell renal cell carcinoma: Mechanisms and therapeutic potential

利用甲基亚硒酸/硒代-L-蛋氨酸靶向转化生长因子-β1治疗透明细胞肾细胞癌：机制及治疗潜力

期刊:Cancer Treatment and Research Communications
影响因子:2.4
doi:10.1016/j.ctarc.2025.100864
Rataan, Aseel O; Xu, Yan; Geary, Sean M; Zakharia, Yousef; Kamel, Eman S; Rustum, Youcef M; Salem, Aliasger K
肿瘤
肾癌
肿瘤免疫
细胞生物学
发表日期：2024
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Selenium targets resistance biomarkers enhancing efficacy while reducing toxicity of anti-cancer drugs: preclinical and clinical development

硒靶向耐药生物标志物，增强抗癌药物疗效并降低其毒性：临床前和临床开发

期刊:Oncotarget
影响因子:
doi:10.18632/oncotarget.24297
Zakharia, Yousef; Bhattacharya, Arup; Rustum, Youcef M
肿瘤
毒理研究
肿瘤免疫
发表日期：2018
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Effects of selenomethionine on acute toxicities from concurrent chemoradiation for inoperable stage III non-small cell lung cancer

硒代蛋氨酸对不可手术的III期非小细胞肺癌同步放化疗急性毒性的影响

期刊:World Journal of Clinical Oncology
影响因子:3.2
doi:10.5306/wjco.v6.i5.156
Mix, Michael; Ramnath, Nithya; Gomez, Jorge; de Groot, Charles; Rajan, Saju; Dibaj, Shiva; Tan, Wei; Rustum, Youcef; Jameson, Michael B; Singh, Anurag K
肺癌
肿瘤
肿瘤免疫
细胞生物学
毒理研究
发表日期：2015
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Randomized phase II trial of selenomethionine as a modulator of efficacy and toxicity of chemoradiation in squamous cell carcinoma of the head and neck

硒代蛋氨酸作为头颈部鳞状细胞癌放化疗疗效和毒性调节剂的随机II期试验

期刊:World Journal of Clinical Oncology
影响因子:3.2
doi:10.5306/wjco.v6.i5.166
Mix, Michael; Singh, Anurag K; Tills, Michael; Dibaj, Shiva; Groman, Adrienne; Jaggernauth, Wainwright; Rustum, Youcef; Jameson, Michael B
细胞生物学
肿瘤
毒理研究
肿瘤免疫
发表日期：2015
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Prolyl hydroxylase 2 dependent and Von-Hippel-Lindau independent degradation of Hypoxia-inducible factor 1 and 2 alpha by selenium in clear cell renal cell carcinoma leads to tumor growth inhibition

在透明细胞肾细胞癌中，硒通过脯氨酰羟化酶 2 依赖性和非 Von-Hippel-Lindau 途径降解缺氧诱导因子 1 和 2α，从而抑制肿瘤生长。

期刊:BMC Cancer
影响因子:3.4
doi:10.1186/1471-2407-12-293
Chintala, Sreenivasulu; Najrana, Tanbir; Toth, Karoly; Cao, Shousong; Durrani, Farukh A; Pili, Roberto; Rustum, Youcef M
肿瘤
肾癌
肿瘤免疫
细胞生物学
发表日期：2012
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A novel small molecule FL118 that selectively inhibits survivin, Mcl-1, XIAP and cIAP2 in a p53-independent manner, shows superior antitumor activity.

一种新型小分子 FL118 以 p53 非依赖的方式选择性抑制 survivin、Mcl-1、XIAP 和 cIAP2，表现出优异的抗肿瘤活性

期刊:PLoS One
影响因子:2.6
doi:10.1371/journal.pone.0045571
Ling Xiang, Cao Shousong, Cheng Qiuying, Keefe James T, Rustum Youcef M, Li Fengzhi
肿瘤
P53
肿瘤免疫
发表日期：2012
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Ugt1a is required for the protective effect of selenium against irinotecan-induced toxicity

Ugt1a是硒发挥其对伊立替康诱导毒性的保护作用所必需的。

期刊:Cancer Chemotherapy and Pharmacology
影响因子:2.3
doi:10.1007/s00280-011-1820-8
Cao, Shousong; Durrani, Farukh A; Rustum, Youcef M; Yu, Y Eugene
毒理研究
发表日期：2012
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Augmented therapeutic efficacy of irinotecan is associated with enhanced drug accumulation

伊立替康疗效的增强与药物蓄积的增加有关。

期刊:Cancer Letters
影响因子:10.1
doi:10.1016/j.canlet.2011.07.023
Azrak, Rami G; Cao, Shousong; Durrani, Farukh A; Toth, Karoly; Bhattacharya, Arup; Rustum, Youcef M
发表日期：2011
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Bevacizumab enhances the therapeutic efficacy of Irinotecan against human head and neck squamous cell carcinoma xenografts

贝伐珠单抗增强伊立替康对人头颈部鳞状细胞癌异种移植瘤的治疗效果

期刊:Oral Oncology
影响因子:3.9
doi:10.1016/j.oraloncology.2011.04.001
Cao, Shousong; Durrani, Farukh A; Toth, Karoly; Rustum, Youcef M; Seshadri, Mukund
细胞生物学
肿瘤
肿瘤免疫
发表日期：2011
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