Rustum Youcef M相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

Targeting transforming growth factor-β1 by methylseleninic acid/seleno-L-methionine in clear cell renal cell carcinoma: Mechanisms and therapeutic potential

利用甲基亚硒酸/硒代-L-蛋氨酸靶向转化生长因子-β1治疗透明细胞肾细胞癌：机制及治疗潜力

期刊:Cancer Treatment and Research Communications

影响因子:2.4

doi:10.1016/j.ctarc.2025.100864

Rataan, Aseel O; Xu, Yan; Geary, Sean M; Zakharia, Yousef; Kamel, Eman S; Rustum, Youcef M; Salem, Aliasger K

细胞生物学

发表日期：2024

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Selenium targets resistance biomarkers enhancing efficacy while reducing toxicity of anti-cancer drugs: preclinical and clinical development

硒靶向耐药生物标志物，增强抗癌药物疗效并降低其毒性：临床前和临床开发

期刊:Oncotarget

doi:10.18632/oncotarget.24297

Zakharia, Yousef; Bhattacharya, Arup; Rustum, Youcef M

发表日期：2018

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Prolyl hydroxylase 2 dependent and Von-Hippel-Lindau independent degradation of Hypoxia-inducible factor 1 and 2 alpha by selenium in clear cell renal cell carcinoma leads to tumor growth inhibition

在透明细胞肾细胞癌中，硒通过脯氨酰羟化酶 2 依赖性和非 Von-Hippel-Lindau 途径降解缺氧诱导因子 1 和 2α，从而抑制肿瘤生长。

期刊:BMC Cancer

影响因子:3.4

doi:10.1186/1471-2407-12-293

Chintala, Sreenivasulu; Najrana, Tanbir; Toth, Karoly; Cao, Shousong; Durrani, Farukh A; Pili, Roberto; Rustum, Youcef M

细胞生物学

发表日期：2012

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A novel small molecule FL118 that selectively inhibits survivin, Mcl-1, XIAP and cIAP2 in a p53-independent manner, shows superior antitumor activity.

一种新型小分子 FL118 以 p53 非依赖的方式选择性抑制 survivin、Mcl-1、XIAP 和 cIAP2，表现出优异的抗肿瘤活性

期刊:PLoS One

影响因子:2.6

doi:10.1371/journal.pone.0045571

Ling Xiang, Cao Shousong, Cheng Qiuying, Keefe James T, Rustum Youcef M, Li Fengzhi

发表日期：2012

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Ugt1a is required for the protective effect of selenium against irinotecan-induced toxicity

Ugt1a是硒发挥其对伊立替康诱导毒性的保护作用所必需的。

期刊:Cancer Chemotherapy and Pharmacology

影响因子:2.3

doi:10.1007/s00280-011-1820-8

Cao, Shousong; Durrani, Farukh A; Rustum, Youcef M; Yu, Y Eugene

发表日期：2012

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Augmented therapeutic efficacy of irinotecan is associated with enhanced drug accumulation

伊立替康疗效的增强与药物蓄积的增加有关。

期刊:Cancer Letters

影响因子:10.1

doi:10.1016/j.canlet.2011.07.023

Azrak, Rami G; Cao, Shousong; Durrani, Farukh A; Toth, Karoly; Bhattacharya, Arup; Rustum, Youcef M

发表日期：2011

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Bevacizumab enhances the therapeutic efficacy of Irinotecan against human head and neck squamous cell carcinoma xenografts

贝伐珠单抗增强伊立替康对人头颈部鳞状细胞癌异种移植瘤的治疗效果

期刊:Oral Oncology

影响因子:3.9

doi:10.1016/j.oraloncology.2011.04.001

Cao, Shousong; Durrani, Farukh A; Toth, Karoly; Rustum, Youcef M; Seshadri, Mukund

细胞生物学

发表日期：2011

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Double immunohistochemical staining method for HIF-1alpha and its regulators PHD2 and PHD3 in formalin-fixed paraffin-embedded tissues

采用双重免疫组织化学染色法检测福尔马林固定石蜡包埋组织中的HIF-1α及其调节因子PHD2和PHD3

doi:10.1097/PAI.0b013e3181d6bd59

Vaughan, Mary M; Toth, Karoly; Chintala, Sreenivasulu; Rustum, Youcef M

免疫/内分泌

发表日期：2010

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Architectural heterogeneity in tumors caused by differentiation alters intratumoral drug distribution and affects therapeutic synergy of antiangiogenic organoselenium compound

肿瘤分化引起的结构异质性会改变肿瘤内药物分布，并影响抗血管生成有机硒化合物的治疗协同作用。

期刊:Journal of Oncology

doi:10.1155/2010/396286

Rustum, Youcef M; Tóth, Károly; Seshadri, Mukund; Sen, Arindam; Durrani, Farukh A; Stott, Emily; Morrison, Carl D; Cao, Shousong; Bhattacharya, Arup

发表日期：2010

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A phase I, pharmacokinetic and pharmacodynamic study on vorinostat in combination with 5-fluorouracil, leucovorin, and oxaliplatin in patients with refractory colorectal cancer.

一项针对难治性结直肠癌患者的伏立诺他联合 5-氟尿嘧啶、亚叶酸钙和奥沙利铂的 I 期药代动力学和药效学研究

期刊:Clinical Cancer Research

影响因子:10.2

doi:10.1158/1078-0432.CCR-08-2999

Fakih Marwan G, Pendyala Lakshmi, Fetterly Gerald, Toth Karoli, Zwiebel James A, Espinoza-Delgado Igor, Litwin Alan, Rustum Youcef M, Ross Mary Ellen, Holleran Julianne L, Egorin Merrill J

发表日期：2009

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