日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

CD8+ T cells contribute to diet-induced memory deficits in aged male rats

CD8+ T细胞在老年雄性大鼠的饮食诱导性记忆缺陷中发挥作用

Michael J Butler ,Shouvonik Sengupta ,Stephanie M Muscat ,Stephanie A Amici ,Rebecca G Biltz ,Nicholas P Deems ,Piyush Dravid ,Sabrina Mackey-Alfonso ,Haanya Ijaz ,Menaz N Bettes ,Jonathan P Godbout ,Amit Kapoor ,Mireia Guerau-de-Arellano ,Ruth M Barrientos

Selective TLR4 Antagonism Prevents and Reverses Morphine-Induced Persistent Postoperative Cognitive Dysfunction, Dysregulation of Synaptic Elements, and Impaired BDNF Signaling in Aged Male Rats

选择性 TLR4 拮抗剂可预防和逆转老年雄性大鼠吗啡引起的持续性术后认知功能障碍、突触元素失调和 BDNF 信号传导受损

Stephanie M Muscat, Nicholas P Deems, Michael J Butler, Emmanuel A Scaria, Menaz N Bettes, Sean P Cleary, Ross H Bockbrader, Steven F Maier, Ruth M Barrientos

Dietary fatty acids differentially impact phagocytosis, inflammatory gene expression, and mitochondrial respiration in microglial and neuronal cell models

膳食脂肪酸对小胶质细胞和神经元细胞模型中的吞噬作用、炎症基因表达和线粒体呼吸有不同的影响

Michael J Butler, Sabrina E Mackey-Alfonso, Nashali Massa, Kedryn K Baskin, Ruth M Barrientos

Young adult and aged female rats are vulnerable to amygdala-dependent, but not hippocampus-dependent, memory impairment following short-term high-fat diet

短期高脂饮食后,年轻和老年雌性大鼠容易出现依赖杏仁核而非海马体的记忆障碍

Stephanie M Muscat, Michael J Butler, Sabrina E Mackey-Alfonso, Ruth M Barrientos

Aging and an Immune Challenge Interact to Produce Prolonged, but Not Permanent, Reductions in Hippocampal L-LTP and mBDNF in a Rodent Model with Features of Delirium

在具有谵妄特征的啮齿动物模型中,衰老和免疫挑战相互作用导致海马 L-LTP 和 mBDNF 长期(但不是永久性)减少

Naoto Tanaka, Giuseppe P Cortese, Ruth M Barrientos, Steven F Maier, Susan L Patterson

High-fat diet and aging interact to produce neuroinflammation and impair hippocampal- and amygdalar-dependent memory

高脂饮食和衰老相互作用,产生神经炎症,损害海马和杏仁核依赖性记忆

Sarah J Spencer, Heather D'Angelo, Alita Soch, Linda R Watkins, Steven F Maier, Ruth M Barrientos

The Alarmin HMGB1 Mediates Age-Induced Neuroinflammatory Priming

警报蛋白 HMGB1 介导年龄诱导的神经炎症启动

Laura K Fonken, Matthew G Frank, Meagan M Kitt, Heather M D'Angelo, Diana M Norden, Michael D Weber, Ruth M Barrientos, Jonathan P Godbout, Linda R Watkins, Steven F Maier

Glucocorticoids Mediate Short-Term High-Fat Diet Induction of Neuroinflammatory Priming, the NLRP3 Inflammasome, and the Danger Signal HMGB1

糖皮质激素介导短期高脂饮食诱导的神经炎症启动、NLRP3 炎症小体和危险信号 HMGB1

Julia L Sobesky, Heather M D'Angelo, Michael D Weber, Nathan D Anderson, Matthew G Frank, Linda R Watkins, Steven F Maier, Ruth M Barrientos

Greater glucocorticoid receptor activation in hippocampus of aged rats sensitizes microglia

老年大鼠海马中糖皮质激素受体活性增强,使小胶质细胞敏感

Ruth M Barrientos, Vanessa M Thompson, Meagan M Kitt, Jose Amat, Matthew W Hale, Matthew G Frank, Nicole Y Crysdale, Christopher E Stamper, Patrick A Hennessey, Linda R Watkins, Robert L Spencer, Christopher A Lowry, Steven F Maier

Aging and a peripheral immune challenge interact to reduce mature brain-derived neurotrophic factor and activation of TrkB, PLCgamma1, and ERK in hippocampal synaptoneurosomes

衰老和外周免疫挑战相互作用,降低成熟的脑源性神经营养因子以及海马突触神经小体中 TrkB、PLCgamma1 和 ERK 的激活

Giuseppe P Cortese, Ruth M Barrientos, Steven F Maier, Susan L Patterson