日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

TIMEPOINT, a phase 1 study combining MTL-CEBPA with pembrolizumab, supports the immunomodulatory effect of MTL-CEBPA in solid tumors

TIMEPOINT 是一项将 MTL-CEBPA 与帕博利珠单抗联合使用的 1 期研究,该研究支持 MTL-CEBPA 在实体瘤中的免疫调节作用。

Ruth Plummer ,Mikael H Sodergren ,Rose Hodgson ,Bríd M Ryan ,Nina Raulf ,Joanna P Nicholls ,Vikash Reebye ,Jon Voutila ,Laura Sinigaglia ,Tim Meyer ,David J Pinato ,Debashis Sarker ,Bristi Basu ,Sarah Blagden ,Natalie Cook ,Thomas R Jeffrey Evans ,Jeffrey Yachnin ,Cheng E Chee ,Daneng Li ,Anthony El-Khoueiry ,Maria Diab ,Kai-Wen Huang ,Madhava Pai ,Duncan Spalding ,Thomas Talbot ,Marcus S Noel ,Bridget Keenan ,Devalingam Mahalingam ,Min-Sun Song ,Mélanie Grosso ,Denis Arnaud ,Aurelie Auguste ,Dimitris Zacharoulis ,Jan Storkholm ,Iain McNeish ,Robert Habib ,John J Rossi ,Nagy A Habib

Camonsertib in DNA damage response-deficient advanced solid tumors: phase 1 trial results

Camonsertib 在 DNA 损伤反应缺陷的晚期实体肿瘤中的应用:第一阶段试验结果

Timothy A Yap, Elisa Fontana, Elizabeth K Lee, David R Spigel, Martin Højgaard, Stephanie Lheureux, Niharika B Mettu, Benedito A Carneiro, Louise Carter, Ruth Plummer, Gregory M Cote, Funda Meric-Bernstam, Joseph O'Connell, Joseph D Schonhoft, Marisa Wainszelbaum, Adrian J Fretland, Peter Manley #, 

Programmed cell death-1 receptor-mediated regulation of Tbet+NK1.1- innate lymphoid cells within the tumor microenvironment

程序性细胞死亡-1 受体介导的肿瘤微环境内 Tbet+NK1.1- 先天淋巴细胞的调节

Jing Xuan Lim, Chester Y Lai, Grace E Mallett, David McDonald, Gillian Hulme, Stephanie Laba, Andrew Shapanis, Megan Payne, Warren Patterson, Michael Alexander, Jonathan Coxhead, Andrew Filby, Ruth Plummer, Penny E Lovat, Giuseppe Sciume, Eugene Healy, Shoba Amarnath

Upregulation of C/EBPα Inhibits Suppressive Activity of Myeloid Cells and Potentiates Antitumor Response in Mice and Patients with Cancer

C/EBPα 的上调可抑制髓系细胞的抑制活性并增强小鼠和癌症患者的抗肿瘤反应

Ayumi Hashimoto #, Debashis Sarker #, Vikash Reebye #, Sheba Jarvis, Mikael H Sodergren, Andrew Kossenkov, Emilio Sanseviero, Nina Raulf, Jenni Vasara, Pinelopi Andrikakou, Tim Meyer, Kai-Wen Huang, Ruth Plummer, Cheng E Chee, Duncan Spalding, Madhava Pai, Shahid Khan, David J Pinato, Rohini Sharma,

The Novel Nucleoside Analogue ProTide NUC-7738 Overcomes Cancer Resistance Mechanisms In Vitro and in a First-In-Human Phase I Clinical Trial

新型核苷类似物 ProTide NUC-7738 在体外和首次人体 I 期临床试验中克服了癌症耐药机制

Hagen Schwenzer, Erica De Zan, Mustafa Elshani, Ruud van Stiphout, Mary Kudsy, Josephine Morris, Valentina Ferrari, In Hwa Um, James Chettle, Farasat Kazmi, Leticia Campo, Alistair Easton, Sebastian Nijman, Michaela Serpi, Stefan Symeonides, Ruth Plummer, David J Harrison, Gareth Bond, Sarah P Blagd

Ventilation bundle compliance in two Australian intensive care units: An observational study

澳大利亚两家重症监护病房通气方案依从性:一项观察性研究

Madhuvu, Auxillia; Endacott, Ruth; Plummer, Virginia; Morphet, Julia

Cancer immunotherapy and its potential cardiac complications

癌症免疫疗法及其潜在的心脏并发症

Findlay, Simon G; Plummer, Ruth; Plummer, Chris

Inhibition of ATR acutely sensitizes acute myeloid leukemia cells to nucleoside analogs that target ribonucleotide reductase

ATR 的抑制可使急性髓系白血病细胞对靶向核苷酸还原酶的核苷类似物产生急性敏感性

Sarah E Fordham, Helen J Blair, Claire J Elstob, Ruth Plummer, Yvette Drew, Nicola J Curtin, Olaf Heidenreich, Deepali Pal, David Jamieson, Catherine Park, John Pollard, Scott Fields, Paul Milne, Graham H Jackson, Helen J Marr, Tobias Menne, Gail L Jones, James M Allan

High-resolution imaging for the detection and characterisation of circulating tumour cells from patients with oesophageal, hepatocellular, thyroid and ovarian cancers

高分辨率成像用于检测和表征食道癌、肝细胞癌、甲状腺癌和卵巢癌患者的循环肿瘤细胞

Barry M Dent, Laura F Ogle, Rachel L O'Donnell, Nicholas Hayes, Ujjal Malik, Nicola J Curtin, Alan V Boddy, E Ruth Plummer, Richard J Edmondson, Helen L Reeves, Felicity E B May, David Jamieson

mTORC1 and DNA-PKcs as novel molecular determinants of sensitivity to Chk1 inhibition

mTORC1 和 DNA-PKcs 是 Chk1 抑制敏感性的新分子决定因素

Andrew J Massey, Peter Stephens, Rebecca Rawlinson, Lauren McGurk, Ruth Plummer, Nicola J Curtin