日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Additive Effects of Dorzagliatin and Glucagon-Like Peptide 1 Receptor Agonism in a Novel Mouse Model of GCK-MODY and in Obese db/db Mice.

多扎格列汀和胰高血糖素样肽 1 受体激动剂在 GCK-MODY 新型小鼠模型和肥胖 db/db 小鼠中的叠加效应。

Salazar Shadai, Delgadillo-Silva Luis Fernando, Carapeto Priscila, Kenfaoui Mohamed Mourad, Dakessian Karen, Melhem Rana, Provencher-Girard Audrey, Ostinelli Giada, Turgeon Julie, Kaci Imane, Migneault Francis, Huising Mark O, Hébert Marie-Josée, Chaker-Margot Malik, Rutter Guy A

STARD10 regulates human pancreatic β cell differentiation and triglyceride metabolism

STARD10 调控人胰岛β细胞分化和甘油三酯代谢

Tan, Wei Xuan; Amirruddin, Nur Shabrina; Lim, Euodia Xi Hui; Hu, Ming; Muralidharan, Sneha; Benke, Peter I; Torta, Federico; Hoon, Shawn; Soetedjo, Andreas Alvin P; Lau, Hwee Hui; Ng, Natasha H J; Rutter, Guy A; Teo, Adrian Kee Keong

Pancreatic islet cell calcium ion imaging at single-cell resolution: functional identification of first-responder, highly connected ("hub"), and leader beta-cells

单细胞分辨率的胰岛细胞钙离子成像:对首发反应细胞、高度连接(“枢纽”)和领头β细胞进行功能性鉴定

Delgadillo-Silva, Luis Fernando; Ostinelli, Giada; Provencher-Girard, Audrey; Salazar, Shadai; Melhem, Rana; Rutter, Guy A

MTFP1 preserves β-cell cristae structure and bioenergetics to ensure insulin release and glucose homeostasis

MTFP1 维持 β 细胞嵴结构和生物能量,以确保胰岛素释放和葡萄糖稳态。

Sarwat, Sunehera; Alen, Rosa; Wu, Zhiyi; Zhang, Chuyue; Paszek, Michael; Yang, MingMing; Ostinelli, Giada; Mihalovits, Alina; Baker, Bell; Wai, Timothy; Rutter, Guy A; Rodriguez, Tristan A; Martinez-Sanchez, Aida

LONP1 regulation of mitochondrial protein folding provides insight into beta cell failure in type 2 diabetes.

LONP1 对线粒体蛋白折叠的调控为 2 型糖尿病中 β 细胞功能衰竭提供了见解

Li Jin, Deng Yamei, Gasser Marie, Zhu Jie, Walker Emily M, Sidarala Vaibhav, Reck Emma C, Hubers Dre L, Pasmooij Mabelle B, Shin Chun-Shik, Bandesh Khushdeep, Motakis Eftyhmios, Nargund Siddhi, Kursawe Romy, Basrur Venkatesha, Nesvizhskii Alexey I, Stitzel Michael L, Chan David C, Rutter Guy A, Soleimanpour Scott A

I-BET151 modulates glucokinase gene expression and beta cell function in part through changes in FOXO1 expression

I-BET151通过改变FOXO1的表达,部分调节葡萄糖激酶基因表达和β细胞功能。

Ho, Qing Wei Calvin; Miller, James A; Gunaseelan, Divya; Chelliah, Rosi; Babu, Hemapriya Jayaranga; Chew, Xin Yan; Devaraj, Surabhi; Tay, Vanessa Shiyun; Kong, Dewei; Wang, Xiaoling; Tan, Daphne Yuanling; Rutter, Guy A; Lee, Bernett; Teo, Adrian Kee Keong; Ali, Yusuf

Effects of SGLT2 ablation or inhibition on corticosterone secretion in high-fat-fed mice: exploring a nexus with cytokine levels

SGLT2 缺失或抑制对高脂饮食小鼠皮质酮分泌的影响:探索其与细胞因子水平的关联

Brisnovali, Niki F; Franco, Isabelle; Abdelgawwad, Amira; Tsou, Hio Lam Phoebe; Cao, Thong Huy; McDonald, John; Riva, Antonio; Rutter, Guy A; Akalestou, Elina

A high-throughput screening approach to discover potential colorectal cancer chemotherapeutics: repurposing drugs to identify novel disruptors of 14-3-3 proteins.

利用高通量筛选方法发现潜在的结直肠癌化疗药物:重新利用药物来识别 14-3-3 蛋白的新型破坏剂。

He Siyi, Meister Daniel, Khan Samra, Mohammadzadeh Azam, Delgadillo Silva Luis, Rutter Guy A, Trant John F, Lim Gareth E

Editorial: In vivo magnetic resonance imaging of metabolic disorders

社论:代谢紊乱的体内磁共振成像

Tang, An; Lepage, Martin; Rutter, Guy A; Carpentier, André C

Severe neonatal hypotonia due to SLC30A5 variant affecting function of ZnT5 zinc transporter

SLC30A5 变异影响 ZnT5 锌转运蛋白的功能,导致新生儿严重肌张力低下。

Dolgin, Vadim; Chabosseau, Pauline; Bistritzer, Jacob; Noyman, Iris; Staretz-Chacham, Orna; Wormser, Ohad; Hadar, Noam; Eskin-Schwartz, Marina; Kanengisser-Pines, Bibi; Narkis, Ginat; Abramsky, Ramy; Shany, Eilon; Rutter, Guy A; Marks, Kyla; Birk, Ohad S