Combining a CAR and a chimeric costimulatory receptor enhances T cell sensitivity to low antigen density and promotes persistence
将CAR与嵌合共刺激受体结合，可增强T细胞对低抗原密度的敏感性并促进其持久性。
期刊:Science Translational Medicine
影响因子:15.8
doi:10.1126/scitranslmed.abh1962
Afroditi Katsarou,Maria Sjöstrand,Jyoti Naik,Jorge Mansilla-Soto,Dionysia Kefala,Georgios Kladis,Alexandros Nianias,Ruud Ruiter,Renée Poels,Irene Sarkar,Yash R Patankar,Elena Merino,Rogier M Reijmers,Kristine A Frerichs,Huipin Yuan,Joost de Bruijn,Dina Stroopinsky,David Avigan,Niels W C J van de Donk,Sonja Zweegman,Tuna Mutis,Michel Sadelain,Richard W J Groen,Maria Themeli
