日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Large-Scale Production of LGR5-Positive Bipotential Human Liver Stem Cells

大规模生产LGR5阳性双潜能人类肝脏干细胞

Kerstin Schneeberger, Natalia Sánchez-Romero, Shicheng Ye, Frank G van Steenbeek, Loes A Oosterhoff, Iris Pla Palacin, Chen Chen, Monique E van Wolferen, Gilles van Tienderen, Ruby Lieshout, Haaike Colemonts-Vroninks, Imre Schene, Ruurdtje Hoekstra, Monique M A Verstegen, Luc J W van der Laan, Louis

End-stage liver failure: filling the treatment gap at the intensive care unit

终末期肝衰竭:填补重症监护病房的治疗缺口

Chamuleau, Robert A F M; Hoekstra, Ruurdtje

Improved oxygenation dramatically alters metabolism and gene expression in cultured primary mouse hepatocytes

氧合作用的改善显著改变了培养的原代小鼠肝细胞的代谢和基因表达。

Gilglioni, Eduardo H; Chang, Jung-Chin; Duijst, Suzanne; Go, Simei; Adam, Aziza A A; Hoekstra, Ruurdtje; Verhoeven, Arthur J; Ishii-Iwamoto, Emy L; Oude Elferink, Ronald P J

Oxygen drives hepatocyte differentiation and phenotype stability in liver cell lines

氧气驱动肝细胞分化和肝细胞系表型稳定性

Martien van Wenum, Aziza A A Adam, Vincent A van der Mark, Jung-Chin Chang, Manon E Wildenberg, Erik J Hendriks, Aldo Jongejan, Perry D Moerland, Thomas M van Gulik, Ronald P Oude Elferink, Robert A F M Chamuleau, Ruurdtje Hoekstra

A practice-changing culture method relying on shaking substantially increases mitochondrial energy metabolism and functionality of human liver cell lines.

一种改变培养方法的摇晃培养方法显著提高了人类肝细胞系的线粒体能量代谢和功能

Adam Aziza A A, van der Mark Vincent A, Donkers Joanne M, Wildenberg Manon E, Oude Elferink Ronald P J, Chamuleau Robert A F M, Hoekstra Ruurdtje

Selecting Cells for Bioartificial Liver Devices and the Importance of a 3D Culture Environment: A Functional Comparison between the HepaRG and C3A Cell Lines.

生物人工肝装置细胞的选择及3D培养环境的重要性:HepaRG和C3A细胞系的功能比较

van Wenum Martien, Adam Aziza A A, Hakvoort Theodorus B M, Hendriks Erik J, Shevchenko Valery, van Gulik Thomas M, Chamuleau Robert A F M, Hoekstra Ruurdtje

Human fetal liver cells for regulated ex vivo erythropoietin gene therapy

用于调控体外促红细胞生成素基因治疗的人类胎肝细胞

El Filali, Ebtisam; Duijst, Suzanne; Hiralall, Johan K; Legrand, Nicolas; van Gulik, Thomas; Hoekstra, Ruurdtje; Seppen, Jurgen

Novel immortalized human fetal liver cell line, cBAL111, has the potential to differentiate into functional hepatocytes

新型永生化人胎肝细胞系 cBAL111 具有分化为功能性肝细胞的潜力

Tanja Deurholt, Niek P van Til, Aniska A Chhatta, Lysbeth ten Bloemendaal, Ruth Schwartlander, Catherine Payne, John N Plevris, Igor M Sauer, Robert Afm Chamuleau, Ronald Pj Oude Elferink, Jurgen Seppen, Ruurdtje Hoekstra

Clinical application of bioartificial liver support systems

生物人工肝支持系统的临床应用

van de Kerkhove, Maarten Paul; Hoekstra, Ruurdtje; Chamuleau, Robert A F M; van Gulik, Thomas M