日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Uncovering newly identified aldehyde dehydrogenase 2 genetic variants that lead to acetaldehyde accumulation after an alcohol challenge

发现新发现的乙醛脱氢酶 2 基因变异,导致酒精刺激后乙醛积累

Freeborn Rwere, Joseph R White, Rafaela C R Hell, Xuan Yu, Xiaocong Zeng, Leslie McNeil, Kevin N Zhou, Martin S Angst, Che-Hong Chen, Daria Mochly-Rosen, Eric R Gross

The JPET Editorial Fellowship: Opening the Blinds to the Peer Review and Editorial Process

JPET编辑奖学金:揭开同行评审和编辑过程的神秘面纱

Ladumor, Mayur K; Mielnik, Catharine A; Peterson, Cristina D; Rwere, Freeborn; Gross, Eric R

A flexible linker of 8-amino acids between the membrane binding segment and the FMN domain of cytochrome P450 reductase is necessary for optimal activity

细胞色素P450还原酶膜结合片段与FMN结构域之间由8个氨基酸组成的柔性连接肽对于其最佳活性至关重要。

Rwere, Freeborn; Cartee, Naw May P; Yang, Yuting; Waskell, Lucy

SGLT2 inhibitor ameliorates endothelial dysfunction associated with the common ALDH2 alcohol flushing variant

SGLT2抑制剂可改善与常见的ALDH2酒精潮红变异相关的内皮功能障碍

Guo, Hongchao; Yu, Xuan; Liu, Yu; Paik, David T; Justesen, Johanne Marie; Chandy, Mark; Jahng, James W S; Zhang, Tiejun; Wu, Weijun; Rwere, Freeborn; Zhao, Shane Rui; Pokhrel, Suman; Shivnaraine, Rabindra V; Mukherjee, Souhrid; Simon, Daniel J; Manhas, Amit; Zhang, Angela; Chen, Che-Hong; Rivas, Manuel A; Gross, Eric R; Mochly-Rosen, Daria; Wu, Joseph C

A human TRPV1 genetic variant within the channel gating domain regulates pain sensitivity in rodents

通道门控域内的人类 TRPV1 基因变异可调节啮齿动物的疼痛敏感性

Shufang He, Vanessa O Zambelli, Pritam Sinharoy, Laura Brabenec, Yang Bian, Freeborn Rwere, Rafaela Cr Hell, Beatriz Stein Neto, Barbara Hung, Xuan Yu, Meng Zhao, Zhaofei Luo, Chao Wu, Lijun Xu, Katrin J Svensson, Stacy L McAllister, Creed M Stary, Nana-Maria Wagner, Ye Zhang, Eric R Gross

Natural products for the treatment and management of diabetes mellitus in Zimbabwe-a review

津巴布韦糖尿病治疗和管理中的天然产品综述

Usai, Remigio; Majoni, Stephen; Rwere, Freeborn

Influence of CYP2C19*17 Genetic Polymorphism on the Steady-State Concentration of Escitalopram in Patients with Recurrent Depressive Disorder

CYP2C19*17基因多态性对复发性抑郁症患者艾司西酞普兰稳态浓度的影响

Zastrozhin, M S; Skryabin, VYu; Rwere, F; Petukhov, A E; Pankratenko, E P; Pozdniakov, S A; Ivanchenko, V A; Noskov, V V; Zaytsev, I A; Vinokurova, N V; Horyaev, D S; Vlasovskih, R V; Bryun, E A; Sychev, D A

The FMN "140s Loop" of Cytochrome P450 Reductase Controls Electron Transfer to Cytochrome P450

细胞色素P450还原酶的FMN“140s环”控制电子向细胞色素P450的传递

Rwere, Freeborn; Im, Sangchoul; Waskell, Lucy

Structural and Kinetic Studies of Asp632 Mutants and Fully Reduced NADPH-Cytochrome P450 Oxidoreductase Define the Role of Asp632 Loop Dynamics in the Control of NADPH Binding and Hydride Transfer

对 Asp632 突变体和完全还原的 NADPH-细胞色素 P450 氧化还原酶的结构和动力学研究揭示了 Asp632 环动力学在控制 NADPH 结合和氢化物转移中的作用

Xia, Chuanwu; Rwere, Freeborn; Im, Sangchoul; Shen, Anna L; Waskell, Lucy; Kim, Jung-Ja P

Mutants of Cytochrome P450 Reductase Lacking Either Gly-141 or Gly-143 Destabilize Its FMN Semiquinone

缺乏 Gly-141 或 Gly-143 的细胞色素 P450 还原酶突变体会使其 FMN 半醌不稳定

Freeborn Rwere, Chuanwu Xia, Sangchoul Im, Mohammad M Haque, Dennis J Stuehr, Lucy Waskell, Jung-Ja P Kim