日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Redox imbalance dictates dependence on GOT1 versus GOT2 for rod photoreceptor health during aging and stress

氧化还原失衡决定了衰老和应激过程中视杆细胞光感受器健康对 GOT1 和 GOT2 的依赖性。

期刊:
影响因子:
doi:10.64898/2026.04.05.716322
Chen, Meini; Weh, Eric; Goswami, Moloy T; Weh, Katherine M; Hager, Heather; Sajjakulnukit, Peter; Weingarten, Avi; Subramanya, Shubha; Miller, Nicholas; Chaudhury, Sraboni; Piraino, Emma; Chandel, Navdeep S; Ryals, Renee C; Lyssiotis, Costas A; Wubben, Thomas J
细胞生物学
衰老
发表日期：2026
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Allogeneic RPE cell suspension manufactured at scale demonstrating preclinical safety and efficacy led to IND approval.

大规模生产的同种异体 RPE 细胞悬液证明了其临床前安全性和有效性，从而获得了 IND 批准

期刊:npj Regenerative Medicine
影响因子:6.5
doi:10.1038/s41536-025-00407-0
Soundararajan Lalitha, Surendran Harshini, Patlolla Niharika, Battu Rajani, Stoddard Jonathan, Arrizabalaga Sebastian, Liu Zengping, Lingam Gopal, Su Xinyi, Ryals Renee C, Pal Rajarshi
细胞生物学
发表日期：2025
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Characterization of the Pank2-/- mouse retinal phenotype as a pre-clinical model for pantothenate kinase-associated neurodegeneration

将 Pank2-/- 小鼠视网膜表型表征为泛酸激酶相关神经退行性疾病的临床前模型

期刊:PLoS One
影响因子:2.6
doi:10.1371/journal.pone.0326866
Su, Grace Li-Na; Jeong, Suh Young; Wafai, Dahlia; Tschetter, Wayne; Zhen, Dolly; Hayflick, Susan J; Ryals, Renee C
信号转导
神经科学
发表日期：2025
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Preformed Vesicle Approach to LNP Manufacturing Enhances Retinal mRNA Delivery.

预成型囊泡法制备LNP可增强视网膜mRNA递送

期刊:Small
影响因子:12.1
doi:10.1002/smll.202400815
Eygeris Yulia, Henderson Michael I, Curtis Allison G, Jozić Antony, Stoddard Jonathan, Reynaga Rene, Chirco Kathleen R, Su Grace Li-Na, Neuringer Martha, Lauer Andreas K, Ryals Renee C, Sahay Gaurav
其它
囊泡
发表日期：2024
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Thiophene-based lipids for mRNA delivery to pulmonary and retinal tissues

基于噻吩的脂质体用于将mRNA递送至肺部和视网膜组织

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2307813120
Eygeris, Yulia; Gupta, Mohit; Kim, Jeonghwan; Jozic, Antony; Gautam, Milan; Renner, Jonas; Nelson, Dylan; Bloom, Elissa; Tuttle, Adam; Stoddard, Jonathan; Reynaga, Rene; Neuringer, Martha; Lauer, Andreas K; Ryals, Renee C; Sahay, Gaurav
发表日期：2024
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Natural history of cone disease in the murine model of Leber congenital amaurosis due to CEP290 mutation: determining the timing and expectation of therapy

CEP290 基因突变引起的 Leber 先天性黑蒙小鼠模型中视锥细胞疾病的自然史：确定治疗时机和预期效果

期刊:PLoS One
影响因子:2.6
doi:10.1371/journal.pone.0092928
Boye, Shannon E; Huang, Wei-Chieh; Roman, Alejandro J; Sumaroka, Alexander; Boye, Sanford L; Ryals, Renee C; Olivares, Melani B; Ruan, Qing; Tucker, Budd A; Stone, Edwin M; Swaroop, Anand; Cideciyan, Artur V; Hauswirth, William W; Jacobson, Samuel G
细胞生物学
发表日期：2014
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Cone specific promoter for use in gene therapy of retinal degenerative diseases

用于视网膜退行性疾病基因治疗的视锥细胞特异性启动子

期刊:Advances in Experimental Medicine and Biology
影响因子:
doi:10.1007/978-1-4614-3209-8_87
Dyka, Frank M; Boye, Sanford L; Ryals, Renee C; Chiodo, Vince A; Boye, Shannon E; Hauswirth, William W
细胞生物学
基因治疗
发表日期：2014
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γ-Secretase inhibition of murine choroidal neovascularization is associated with reduction of superoxide and proinflammatory cytokines.

γ-分泌酶抑制小鼠脉络膜新生血管形成与超氧化物和促炎细胞因子的减少有关

期刊:Investigative Ophthalmology & Visual Science
影响因子:4.7
doi:10.1167/iovs.11-8728
Qi Xiaoping, Cai Jun, Ruan Qing, Liu Li, Boye Sanford L, Chen Zhijuan, Hauswirth William W, Ryals Renee C, Shaw Lynn, Caballero Sergio, Grant Maria B, Boulton Michael E
细胞生物学
炎症
发表日期：2012
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