KDR Amplification Is Associated with VEGF-Induced Activation of the mTOR and Invasion Pathways but does not Predict Clinical Benefit to the VEGFR TKI Vandetanib
KDR 扩增与 VEGF 诱导的 mTOR 和侵袭途径激活有关,但不能预测 VEGFR TKI Vandetanib 的临床益处
期刊:Clinical Cancer Research
影响因子:10
doi:10.1158/1078-0432.CCR-15-1994
Monique B Nilsson, Uma Giri, Jayanthi Gudikote, Ximing Tang, Wei Lu, Hai Tran, Youhong Fan, Andrew Koo, Lixia Diao, Pan Tong, Jing Wang, Roy Herbst, Bruce E Johnson, Andy Ryan, Alan Webster, Philip Rowe, Ignacio I Wistuba, John V Heymach