日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Modular pooled discovery of synthetic knockin sequences to program durable cell therapies

利用模块化集合方法发现合成敲入序列,以编程持久性细胞疗法

Franziska Blaeschke,Yan Yi Chen,Ryan Apathy,Bence Daniel,Andy Y Chen,Peixin Amy Chen,Katalin Sandor,Wenxi Zhang,Zhongmei Li,Cody T Mowery,Tori N Yamamoto,William A Nyberg,Angela To,Ruby Yu,Raymund Bueno,Min Cheol Kim,Ralf Schmidt,Daniel B Goodman,Tobias Feuchtinger,Justin Eyquem,Chun Jimmie Ye,Julia Carnevale,Ansuman T Satpathy,Eric Shifrut,Theodore L Roth,Alexander Marson

Pooled Knockin Targeting for Genome Engineering of Cellular Immunotherapies

用于细胞免疫疗法基因组工程的联合敲入靶向

Theodore L Roth ,P Jonathan Li ,Franziska Blaeschke ,Jasper F Nies ,Ryan Apathy ,Cody Mowery ,Ruby Yu ,Michelle L T Nguyen ,Youjin Lee ,Anna Truong ,Joseph Hiatt ,David Wu ,David N Nguyen ,Daniel Goodman ,Jeffrey A Bluestone ,Chun Jimmie Ye ,Kole Roybal ,Eric Shifrut ,Alexander Marson

Polymer-stabilized Cas9 nanoparticles and modified repair templates increase genome editing efficiency

聚合物稳定的Cas9纳米粒子和修饰的修复模板提高了基因组编辑效率

David N Nguyen #, Theodore L Roth #, P Jonathan Li, Peixin Amy Chen, Ryan Apathy, Murad R Mamedov, Linda T Vo, Victoria R Tobin, Daniel Goodman, Eric Shifrut, Jeffrey A Bluestone, Jennifer M Puck, Francis C Szoka, Alexander Marson

Large dataset enables prediction of repair after CRISPR-Cas9 editing in primary T cells

大型数据集可预测原代 T 细胞中 CRISPR-Cas9 编辑后的修复情况

Ryan T Leenay #, Amirali Aghazadeh #, Joseph Hiatt #, David Tse, Theodore L Roth, Ryan Apathy, Eric Shifrut, Judd F Hultquist, Nevan Krogan, Zhenqin Wu, Giana Cirolia, Hera Canaj, Manuel D Leonetti, Alexander Marson, Andrew P May, James Zou2