Targeting aurora kinases limits tumour growth through DNA damage-mediated senescence and blockade of NF-κB impairs this drug-induced senescence
靶向极光激酶可通过 DNA 损伤介导的衰老来限制肿瘤生长，而阻断 NF-κB 可削弱这种药物引起的衰老
期刊:EMBO Molecular Medicine
影响因子:9
doi:10.1002/emmm.201201378
Yan Liu, Oriana E Hawkins, Yingjun Su, Anna E Vilgelm, Tammy Sobolik, Yee-Mon Thu, Sara Kantrow, Ryan C Splittgerber, Sarah Short, Katayoun I Amiri, Jeffery A Ecsedy, Jeffery A Sosman, Mark C Kelley, Ann Richmond
信号转导
肿瘤
WB
NF-κB
Senescence
Human
p73
