日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Nutrient-driven histone code determines exhausted CD8+ T cell fates

营养驱动的组蛋白密码决定了耗竭的CD8+ T细胞的命运

Shixin Ma ,Michael S Dahabieh ,Thomas H Mann ,Steven Zhao ,Bryan McDonald ,Won-Suk Song ,H Kay Chung ,Yagmur Farsakoglu ,Lizmarie Garcia-Rivera ,Filipe Araujo Hoffmann ,Shihao Xu ,Victor Y Du ,Dan Chen ,Jesse Furgiuele ,Michael A LaPorta ,Emily Jacobs ,Lisa M DeCamp ,Brandon M Oswald ,Ryan D Sheldon ,Abigail E Ellis ,Longwei Liu ,Peixiang He ,Yingxiao Wang ,Cholsoon Jang ,Russell G Jones ,Susan M Kaech

The prostacyclin receptor PTGIR is a NRF2-dependent regulator of CD8+ T cell exhaustion

前列环素受体PTGIR是NRF2依赖性的CD8+ T细胞耗竭调节因子。

Michael S Dahabieh,Lisa M DeCamp,Brandon M Oswald,Susan M Kitchen-Goosen,Zhen Fu,Matthew Vos,Shelby E Compton,Joseph Longo,Nicole M Foy,Kelsey S Williams,Abigail E Ellis,Amy Johnson,Ibukunoluwa Sodiya,Michael Vincent,Hyoungjoo Lee,Chen Yao ,Tuoqi Wu ,Ryan D Sheldon,Connie M Krawczyk,Russell G Jones

Glucose-dependent glycosphingolipid biosynthesis fuels CD8+ T cell function and tumor control

葡萄糖依赖性糖鞘脂生物合成为CD8+ T细胞功能和肿瘤控制提供能量

Joseph Longo ,Lisa M DeCamp ,Brandon M Oswald ,Robert Teis ,Alfredo Reyes-Oliveras ,Michael S Dahabieh ,Abigail E Ellis ,Michael P Vincent ,Hannah Damico ,Kristin L Gallik ,Nicole M Foy ,Shelby E Compton ,Colt D Capan ,Kelsey S Williams ,Corinne R Esquibel ,Zachary B Madaj ,Hyoungjoo Lee ,Dominic G Roy ,Connie M Krawczyk ,Brian B Haab ,Ryan D Sheldon ,Russell G Jones

Nrf2 drives activation-driven expansion of CD4+T cells by modulating glucose and glutamine metabolism

Nrf2通过调节葡萄糖和谷氨酰胺代谢驱动CD4+T细胞的活化驱动扩增。

Aprajita Tripathi ,Debolina Dasgupta ,Michael S Dahabieh ,Rachel Griffard-Smith ,Anil Pant ,Ashlyn Bugbee ,Nanda Kumar Yellapu ,Emily Burt ,Ben H Y Choi ,Abigail E Ellis ,Ryan D Sheldon ,Shailendra Giri ,Devin Koestler ,Russell G Jones ,Viveka Nand Yadav ,Kalyani Pyaram

Mitochondrial fatty acid synthesis and MECR regulate CD4+ T cell function and oxidative metabolism

线粒体脂肪酸合成和MECR调节CD4+ T细胞功能和氧化代谢

KayLee K Steiner,Arissa C Young,Andrew R Patterson,Ayaka Sugiura,McLane J Watson,Samuel E J Preston,Anton Zhelonkin,Erin Q Jennings,Channing Chi,Darren R Heintzman,Andrew P Pahnke,Yasmine T Toudji,Zaid Hatem,Matthew Z Madden,Emily N Arner,Allison E Sewell,Allison K Blount,Richmond Okparaugo,Emilia Fallman,Evan S Krystofiak,Ryan D Sheldon,Katherine N Gibson-Corley,Kelsey Voss,Sara M Nowinski,Russell G Jones,Denis A Mogilenko,Jeffrey C Rathmell

A diverse proteome is present and enzymatically active in metabolite extracts

代谢物提取物中存在多样化的蛋白质组并具有酶活性

Rachel Rae J House #, Molly T Soper-Hopper #, Michael P Vincent, Abigail E Ellis, Colt D Capan, Zachary B Madaj, Emily Wolfrum, Christine N Isaguirre, Carlos D Castello, Amy B Johnson, Martha L Escobar Galvis, Kelsey S Williams, Hyoungjoo Lee, Ryan D Sheldon

Acod1 expression in cancer cells promotes immune evasion through the generation of inhibitory peptides

癌细胞中Acod1的表达通过产生抑制性肽来促进免疫逃逸。

James H Schofield ,Joseph Longo ,Ryan D Sheldon ,Emma Albano ,Abigail E Ellis ,Mark A Hawk ,Sean Murphy ,Loan Duong ,Sharif Rahmy ,Xin Lu ,Russell G Jones ,Zachary T Schafer

NF1 deficiency drives metabolic reprogramming in ER+ breast cancer

NF1缺陷驱动ER+乳腺癌的代谢重编程

Rachel Rae J House ,Elizabeth A Tovar ,Luke N Redlon ,Curt J Essenburg ,Patrick S Dischinger ,Abigail E Ellis ,Ian Beddows ,Ryan D Sheldon ,Evan C Lien ,Carrie R Graveel ,Matthew R Steensma

A high-throughput screening platform for discovering bacterial species and small molecules that modify animal physiology

用于发现改变动物生理的细菌种类和小分子的高通量筛选平台

Kelsie M Nauta, Darrick Gates, Marco Mechan-Llontop, Xiao Wang, Kim Nguyen, Christine N Isaguirre, Megan Genjdar, Ryan D Sheldon, Nicholas O Burton

NRF2-dependent regulation of the prostacyclin receptor PTGIR drives CD8 T cell exhaustion

NRF2 依赖性调节前列环素受体 PTGIR 导致 CD8 T 细胞耗竭

Michael S Dahabieh, Lisa M DeCamp, Brandon M Oswald, Susan M Kitchen-Goosen, Zhen Fu, Matthew Vos, Shelby E Compton, Joseph Longo, Kelsey S Williams, Abigail E Ellis, Amy Johnson, Ibukunoluwa Sodiya, Michael Vincent, Hyoungjoo Lee, Ryan D Sheldon, Connie M Krawczyk, Chen Yao, Tuoqi Wu, Russell G Jon