Analysis of Circulating Cell-Free DNA Identifies Multiclonal Heterogeneity of BRCA2 Reversion Mutations Associated with Resistance to PARP Inhibitors
循环游离 DNA 分析鉴定出与 PARP 抑制剂耐药性相关的 BRCA2 回复突变的多克隆异质性
期刊:Cancer Discovery
影响因子:29.7
doi:10.1158/2159-8290.CD-17-0146
David Quigley, Joshi J Alumkal, Alexander W Wyatt, Vishal Kothari, Adam Foye, Paul Lloyd, Rahul Aggarwal, Won Kim, Eric Lu, Jacob Schwartzman, Kevin Beja, Matti Annala, Rajdeep Das, Morgan Diolaiti, Colin Pritchard, George Thomas, Scott Tomlins, Karen Knudsen, Christopher J Lord, Charles Ryan, Jack