(R)-2-Hydroxyglutarate Inhibits KDM5 Histone Lysine Demethylases to Drive Transformation in IDH-Mutant Cancers
(R)-2-羟基戊二酸抑制 KDM5 组蛋白赖氨酸去甲基化酶，从而促进 IDH 突变癌症的转化
期刊:Cancer Discovery
影响因子:29.7
doi:10.1158/2159-8290.CD-22-0825
Kathryn Gunn, Matti Myllykoski, John Z Cao, Manna Ahmed, Bofu Huang, Betty Rouaisnel, Bill H Diplas, Michael M Levitt, Ryan Looper, John G Doench, Keith L Ligon, Harley I Kornblum, Samuel K McBrayer, Hai Yan, Cihangir Duy, Lucy A Godley, Peppi Koivunen, Julie-Aurore Losman
肿瘤
IHC
Mouse
IgG light chain
