Rybak Jeffrey M相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

Relative contributions of the ERG11(VF125AL) and MRR1A(N647T) mutations to fluconazole resistance in Clade III Candidozyma (Candida) auris clinical isolates

ERG11(VF125AL)和MRR1A(N647T)突变对III型念珠菌（Candidozyma (Candida) auris）临床分离株氟康唑耐药性的相对贡献

期刊:Clinical Microbiology and Infection

影响因子:8.5

doi:10.1016/j.cmi.2025.10.009

Barker, Katherine S; Zhang, Qing; Peters, Tracy L; Rybak, Jeffrey M; Morschhäuser, Joachim; Cuomo, Christina A; Rogers, P David

发表日期：2026

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Mutations in ERG11, TAC1B, and CDR1 reduce fluconazole accumulation in drug-resistant Candidozyma auris isolates

ERG11、TAC1B 和 CDR1 的突变会降低耐药性耳念珠菌分离株中氟康唑的积累。

影响因子:4.7

doi:10.1128/mbio.03957-25

Esquivel, Brooke D; Santos, Amanda; Rybak, Jeffrey M; Santana, Darian J; Rogers, P David; White, Theodore C

发表日期：2026

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Accumulation of Trehalose 6-Phosphate in Candidozyma auris results in Decreased Echinocandin Resistance and Tolerance

耳念珠菌中海藻糖-6-磷酸的积累导致棘白菌素类药物抗性和耐受性降低

期刊:Nature Communications

影响因子:15.7

doi:10.1038/s41467-025-67022-x

Zhu, Qingjuan; Van de Velde, Sien; Wijnants, Stefanie; Carolus, Hans; Jacobs, Stef; Sofras, Dimitrios; Vandecruys, Paul; Van Goethem, Odessa; Feil, Regina; Vergauwen, Rudy; Van Genechten, Wouter; Van den Ende, Wim; Rybak, Jeffrey M; Himmelreich, Uwe; Lunn, John E; Van Dijck, Patrick

发表日期：2025

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A Candidozyma (Candida) auris-Optimized Episomal Plasmid-Induced Cas9-Editing System Reveals the Direct Impact of the S639F-Encoding FKS1 Mutation

一种经耳念珠菌（Candida auris）优化的附加体质粒诱导的Cas9编辑系统揭示了编码S639F突变的FKS1突变的直接影响

期刊:Journal of Infectious Diseases

影响因子:4.5

doi:10.1093/infdis/jiaf285

Doorley, Laura A; Meza-Perez, Vanessa; Jones, Sarah J; Rybak, Jeffrey M

发表日期：2025

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Mutations in TAC1B drive increased CDR1 and MDR1 expression and azole resistance in Candida auris

TAC1B基因突变导致耳念珠菌CDR1和MDR1表达增加以及唑类耐药性

期刊:Antimicrobial Agents and Chemotherapy

影响因子:4.5

doi:10.1128/aac.00300-25

Barker, Katherine S; Santana, Darian J; Zhang, Qing; Peters, Tracy L; Rybak, Jeffrey M; Morschhäuser, Joachim; Cuomo, Christina A; Rogers, P David

发表日期：2025

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Acquired amphotericin B resistance attributed to a mutated ERG3 in Candidozyma auris

耳念珠菌中由 ERG3 突变引起的获得性两性霉素 B 耐药性

期刊:Antimicrobial Agents and Chemotherapy

影响因子:4.5

doi:10.1128/aac.00601-25

Massic, Lauryn; Doorley, Laura A; Jones, Sarah J; Richardson, Irene; Siao, Danielle Denise; Siao, Lauren; Dykema, Philip; Hua, Chi; Schneider, Emily; Cuomo, Christina A; Rogers, P David; Van Hooser, Stephanie; Parker, Josie E; Kelly, Steven L; Hess, David; Rybak, Jeffrey M; Pandori, Mark

发表日期：2025

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A systematic comparison of CRISPR-Cas9 allele editing in Candida auris demonstrates unreliable cassette integration and effective episomal plasmid-based editing

对耳念珠菌中 CRISPR-Cas9 等位基因编辑的系统性比较表明，盒式整合不稳定，而基于游离质粒的编辑则有效。

期刊:Scientific Reports

影响因子:3.9

doi:10.1038/s41598-025-19115-2

Sofras, Dimitrios; Carolus, Hans; Subotić, Ana; Lobo Romero, Celia; Ennis, Craig L; Cuypers, Lize; Lagrou, Katrien; Hernday, Aaron D; Nobile, Clarissa J; Rybak, Jeffrey M; Van Dijck, Patrick

发表日期：2025

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Multi-Omics Analysis of Experimentally Evolved CandidaÂ auris Isolates Reveals Modulation of Sterols, Sphingolipids, and Oxidative Stress in Acquired Amphotericin B Resistance.

对实验进化的耳念珠菌分离株进行多组学分析，揭示了甾醇、鞘脂和氧化应激在获得两性霉素B耐药性中的调节

期刊:Molecular Microbiology

影响因子:2.6

doi:10.1111/mmi.15379

Chauhan Anshu, Carolus Hans, Sofras Dimitrios, Kumar Mohit, Kumar Praveen, Nair Remya, Narayanan Aswathy, Yadav Kusum, Ali Basharat, Biriukov Vladislav, Saini Amandeep, Leaves Ian, Vergauwen Rudy, Romero Celia Lobo, Malavia-Jones Dhara, Singh Ashutosh, Banerjee Atanu, Rudramurthy Shivaprakash M, Chakrabarti Arunaloke, Mondal Alok K, Gaur Naseem A, Sanyal Kaustuv, Rybak Jeffrey M, GabaldÃ³n Toni, Van Dijck Patrick, Gow Neil A R, Prasad Rajendra

发表日期：2025

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Convergent evolution on RBA1 regulates Candidozyma auris host adaptation

RBA1的趋同进化调控耳念珠菌的宿主适应

doi:10.64898/2025.12.04.692421

Doorley, Laura A; La Bella, Alyssa A; Jones, Sarah J; Zhao, Guolei; Asadzadeh, Mohammad; Choudhury, Quanita J; Ahmad, Suhail; Mokaddas, Eiman; Al-Obaid, Inaam; Alfouzan, Wadha; Al-Banwan, Khalifa; O'Meara, Teresa R; Tirado, Felipe H Santiago; Mireles, Ana L Flores; Rybak, Jeffrey M

发表日期：2025

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A Candidozyma ( Candida ) auris -optimized Episomal Plasmid Induced Cas9-editing system reveals the direct impact of the S639F encoding FKS1 mutation

利用耳念珠菌（Candida auris）优化的附加体质粒诱导的Cas9编辑系统揭示了编码FKS1突变的S639F突变的直接影响

doi:10.1101/2025.02.14.638356

Doorley, Laura A; Meza-Perez, Vanessa; Jones, Sarah J; Rybak, Jeffrey M

发表日期：2025

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