日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Autologous cell transplantation for treatment of colorectal aganglionosis in mice

自体细胞移植治疗小鼠大肠神经节缺失症

Weikang Pan #, Ahmed A Rahman #, Takahiro Ohkura, Rhian Stavely, Kensuke Ohishi, Christopher Y Han, Abigail Leavitt, Aki Kashiwagi, Alan J Burns, Allan M Goldstein, Ryo Hotta

Highly neurogenic glia from human and mouse myenteric ganglia generate functional neurons following culture and transplantation into the gut

来自人和小鼠肠肌神经节的高神经源性胶质细胞在体外培养和移植到肠道后可产生功能性神经元。

Jessica L Mueller ,Abigail R Leavitt ,Ahmed A Rahman ,Christopher Y Han ,Leah C Ott ,Narges S Mahdavian ,Simona E Carbone ,Sebastian K King ,Alan J Burns ,Daniel P Poole ,Ryo Hotta ,Allan M Goldstein ,Rhian Stavely

Optogenetic Activation of Cholinergic Enteric Neurons Reduces Inflammation in Experimental Colitis

光遗传学激活胆碱能肠神经元可减轻实验性结肠炎的炎症反应

Ahmed A Rahman ,Rhian Stavely ,Weikang Pan ,Leah Ott ,Kensuke Ohishi ,Takahiro Ohkura ,Christopher Han ,Ryo Hotta ,Allan M Goldstein

Enteric neural stem cell transplant restores gut motility in mice with Hirschsprung disease

肠道神经干细胞移植可恢复患有先天性巨结肠症的小鼠的肠道蠕动

Ahmed A Rahman, Takahiro Ohkura, Sukhada Bhave, Weikang Pan, Kensuke Ohishi, Leah Ott, Christopher Han, Abigail Leavitt, Rhian Stavely, Alan J Burns, Allan M Goldstein, Ryo Hotta

Agrin Inhibition in Enteric Neural Stem Cells Enhances Their Migration Following Colonic Transplantation

肠道神经干细胞中的 Agrin 抑制可增强其在结肠移植后的迁移

Jessica L Mueller, Rhian Stavely, Richard A Guyer, Ádám Soos, Sukhada Bhave, Chris Han, Ryo Hotta, Nandor Nagy, Allan M Goldstein

Single-cell multiome sequencing clarifies enteric glial diversity and identifies an intraganglionic population poised for neurogenesis

单细胞多组测序阐明了肠道神经胶质细胞的多样性,并确定了准备进行神经发生的神经节内群体

Richard A Guyer, Rhian Stavely, Keiramarie Robertson, Sukhada Bhave, Jessica L Mueller, Nicole M Picard, Ryo Hotta, Julia A Kaltschmidt, Allan M Goldstein

Transplanted ENSCs form functional connections with intestinal smooth muscle and restore colonic motility in nNOS-deficient mice

移植的 ENSC 与肠道平滑肌形成功能性连接,并恢复 nNOS 缺陷小鼠的结肠运动

Ryo Hotta, Ahmed Rahman, Sukhada Bhave, Rhian Stavely, Weikang Pan, Shriya Srinivasan, Geoffrey de Couto, Luis Rodriguez-Borlado, Richard Myers, Alan J Burns, Allan M Goldstein

A BODIPY-picolinium-cation conjugate as a blue-light-responsive caged group

一种BODIPY-吡啶鎓阳离子缀合物作为蓝光响应笼状基团

Ieda, Naoya; Nakamura, Akira; Tomita, Natsumi; Ohkubo, Kei; Izumi, Ryo; Hotta, Yuji; Kawaguchi, Mitsuyasu; Kimura, Kazunori; Nakagawa, Hidehiko

Differentiated neuroblastoma cells remain epigenetically poised for de-differentiation to an immature state

分化的神经母细胞瘤细胞在表观遗传学上仍处于去分化为未成熟状态的准备状态。

Richard A Guyer ,Nicole Picard ,Jessica L Mueller ,Kensuke Ohishi ,Abigail Leavitt ,Andrew J Murphy ,Kristine M Cornejo ,Ryo Hotta ,Allan M Goldstein

CXCR4 and CXCL12 signaling regulates the development of extrinsic innervation to the colorectum

CXCR4 和 CXCL12 信号通路调节结直肠外在神经支配的发育

Viktória Halasy ,Emőke Szőcs ,Ádám Soós ,Tamás Kovács ,Nóra Pecsenye-Fejszák ,Ryo Hotta ,Allan M Goldstein ,Nándor Nagy