Quinacrine Inhibits ICAM-1 Transcription by Blocking DNA Binding of the NF-κB Subunit p65 and Sensitizes Human Lung Adenocarcinoma A549 Cells to TNF-α and the Fas Ligand
奎纳克林通过阻断 NF-κB 亚基 p65 的 DNA 结合来抑制 ICAM-1 转录,并使人肺腺癌 A549 细胞对 TNF-α 和 Fas 配体敏感
期刊:International Journal of Molecular Sciences
影响因子:0.7
doi:10.3390/ijms18122603
Misuzu Harada, Kyoko Morimoto, Tetsuya Kondo, Reiko Hiramatsu, Yuji Okina, Ryo Muko, Iyo Matsuda, Takao Kataoka