文献库，生知库 | 链接生命科学的每一步

日期影响因子

Protocol to develop a proximal tubule-on-chip model based on hiPSC-derived kidney organoids for functional analysis of renal transporters

基于hiPSC衍生肾脏类器官构建近端肾小管芯片模型用于肾脏转运蛋白功能分析的方案

期刊:STAR Protocols

影响因子:1.3

doi:10.1016/j.xpro.2025.103777

Cheng Ma,Ramin Banan Sadeghian,Ryosuke Negoro,Kazuya Fujimoto,Toshikazu Araoka,Naoki Ishiguro,Minoru Takasato,Ryuji Yokokawa

发表日期：2025

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Efficient proximal tubule-on-chip model from hiPSC-derived kidney organoids for functional analysis of renal transporters

来自 hiPSC 衍生的肾脏类器官的高效近端小管芯片模型，用于肾脏转运蛋白的功能分析

期刊:iScience

影响因子:4.6

doi:10.1016/j.isci.2024.110760

Cheng Ma, Ramin Banan Sadeghian, Ryosuke Negoro, Kazuya Fujimoto, Toshikazu Araoka, Naoki Ishiguro, Minoru Takasato, Ryuji Yokokawa

发表日期：2024

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Defects in early synaptic formation and neuronal function in Prader-Willi syndrome

普拉德-威利综合征的早期突触形成和神经元功能缺陷

期刊:Scientific Reports

影响因子:3.8

doi:10.1038/s41598-023-39065-x

Shuhei Soeda, Daiki Ito, Tomoe Ogushi, Yui Sano, Ryosuke Negoro, Takuya Fujita, Ryo Saito, Hideo Taniura

发表日期：2023

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Generation of Caco-2 cells with predictable metabolism by CYP3A4, UGT1A1 and CES using the PITCh system

使用 PITCh 系统生成由 CYP3A4、UGT1A1 和 CES 进行可预测代谢的 Caco-2 细胞

期刊:Drug Metabolism and Pharmacokinetics

影响因子:2.7

doi:10.1016/j.dmpk.2023.100497

Naoki Yamada, Ryosuke Negoro, Keita Watanabe, Takuya Fujita

发表日期：2023

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Elucidation of the liver pathophysiology of COVID-19 patients using liver-on-a-chips

使用肝脏芯片阐明 COVID-19 患者的肝脏病理生理学

期刊:PNAS Nexus

影响因子:2.2

doi:10.1093/pnasnexus/pgad029

Sayaka Deguchi, Kaori Kosugi, Rina Hashimoto, Ayaka Sakamoto, Masaki Yamamoto, Rafal P Krol, Peter Gee, Ryosuke Negoro, Takeshi Noda, Takuya Yamamoto, Yu-Suke Torisawa, Miki Nagao, Kazuo Takayama2

发表日期：2023

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Generation of HepG2 Cells with High Expression of Multiple Drug-Metabolizing Enzymes for Drug Discovery Research Using a PITCh System

利用 PITCh 系统生成高表达多种药物代谢酶的 HepG2 细胞，用于药物发现研究

影响因子:5.1

doi:10.3390/cells11101677

Ryosuke Negoro, Mitsuki Tasaka, Sayaka Deguchi, Kazuo Takayama, Takuya Fujita

发表日期：2022

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Vinblastine treatment decreases the undifferentiated cell contamination of human iPSC-derived intestinal epithelial-like cells

长春花碱治疗可减少人类 iPSC 衍生的肠上皮样细胞的未分化细胞污染

期刊:Molecular Therapy-Methods & Clinical Development

doi:10.1016/j.omtm.2021.01.005

Moe Ichikawa, Ryosuke Negoro, Kanae Kawai, Tomoki Yamashita, Kazuo Takayama, Hiroyuki Mizuguchi

细胞生物学

发表日期：2021

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Generation of Human iPSC-Derived Intestinal Epithelial Cell Monolayers by CDX2 Transduction

通过 CDX2 转导生成人类 iPSC 衍生的肠上皮细胞单层

期刊:Cellular and Molecular Gastroenterology and Hepatology

影响因子:7.1

doi:10.1016/j.jcmgh.2019.06.004

Kazuo Takayama, Ryosuke Negoro, Tomoki Yamashita, Kanae Kawai, Moe Ichikawa, Takanori Mori, Noriyuki Nakatsu, Kazuo Harada, Sumito Ito, Hiroshi Yamada, Yoshiyuki Yamaura, Kazumasa Hirata, Seiichi Ishida, Hiroyuki Mizuguchi

细胞生物学

发表日期：2019

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Establishment of SLC15A1/PEPT1-Knockout Human-Induced Pluripotent Stem Cell Line for Intestinal Drug Absorption Studies

建立SLC15A1/PEPT1基因敲除人诱导多能干细胞系用于肠道药物吸收研究

期刊:Molecular Therapy-Methods & Clinical Development

doi:10.1016/j.omtm.2019.11.008

Kanae Kawai, Ryosuke Negoro, Moe Ichikawa, Tomoki Yamashita, Sayaka Deguchi, Kazuo Harada, Kazumasa Hirata, Kazuo Takayama, Hiroyuki Mizuguchi

发育与干细胞

发表日期：2019

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Efficient Generation of Small Intestinal Epithelial-like Cells from Human iPSCs for Drug Absorption and Metabolism Studies

从人类 iPSC 高效生成小肠上皮样细胞用于药物吸收和代谢研究

期刊:Stem Cell Reports

影响因子:5.9

doi:10.1016/j.stemcr.2018.10.019

Ryosuke Negoro, Kazuo Takayama, Kanae Kawai, Kazuo Harada, Fuminori Sakurai, Kazumasa Hirata, Hiroyuki Mizuguchi

发表日期：2018

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