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Mutant PIK3CA as a negative predictive biomarker for treatment with a highly selective PIM1 inhibitor in human colon cancer

突变型PIK3CA作为高选择性PIM1抑制剂治疗人类结肠癌的阴性预测生物标志物

doi:10.1080/15384047.2023.2246208

Park, Yoon Sun; Kim, Joseph; Ryu, Yea Seong; Moon, Jai-Hee; Shin, Yu Jin; Kim, Jeong Hee; Hong, Seung-Woo; Jung, Soo-A; Lee, Seul; Kim, Seung-Mi; Lee, Dae Hee; Kim, Do Yeon; Yun, Hyeseon; You, Ji-Eun; Yoon, Dong Il; Kim, Chul Hee; Koh, Dong-In; Jin, Dong-Hoon

Mutation SVCT2 promotes cell proliferation, invasion and migration in colorectal cancer

SVCT2基因突变促进结直肠癌细胞增殖、侵袭和迁移

期刊:Journal of Cancer

影响因子:3.2

doi:10.7150/jca.57463

Park, Sang-Soo; Ryu, Yea Seong; Koh, Dong-In; Hong, Seung-Woo; Moon, Jai-Hee; Shin, Jae-Sik; Kim, Mi Jin; Kim, Do Yeon; Hong, Jun Ki; Kim, Eun Ho; Jeong, Hong-Rae; Park, Yoon Sun; Kim, Joseph; Kim, Dong Min; Yun, Hyeseon; Shin, Joo-Yeon; Jin, Dong-Hoon

Marine Compound 3-bromo-4,5-dihydroxybenzaldehyde Protects Skin Cells against Oxidative Damage via the Nrf2/HO-1 Pathway

海洋化合物3-溴-4,5-二羟基苯甲醛通过Nrf2/HO-1通路保护皮肤细胞免受氧化损伤

期刊:Marine Drugs

影响因子:5.4

doi:10.3390/md17040234

Ryu, Yea Seong; Fernando, Pincha Devage Sameera Madushan; Kang, Kyoung Ah; Piao, Mei Jing; Zhen, Ao Xuan; Kang, Hee Kyoung; Koh, Young Sang; Hyun, Jin Won

Shikonin Exerts Cytotoxic Effects in Human Colon Cancers by Inducing Apoptotic Cell Death via the Endoplasmic Reticulum and Mitochondria-Mediated Pathways

紫草素通过内质网和线粒体介导的途径诱导细胞凋亡，从而对人结肠癌细胞发挥细胞毒性作用。

期刊:Biomolecules & Therapeutics

影响因子:3.2

doi:10.4062/biomolther.2018.047

Han, Xia; Kang, Kyoung Ah; Piao, Mei Jing; Zhen, Ao Xuan; Hyun, Yu Jae; Kim, Hyun Min; Ryu, Yea Seong; Hyun, Jin Won

7,8-Dihydroxyflavone Protects High Glucose-Damaged Neuronal Cells against Oxidative Stress

7,8-二羟基黄酮可保护高葡萄糖损伤的神经元细胞免受氧化应激损伤

期刊:Biomolecules & Therapeutics

影响因子:3.2

doi:10.4062/biomolther.2018.202

Cho, Suk Ju; Kang, Kyoung Ah; Piao, Mei Jing; Ryu, Yea Seong; Fernando, Pincha Devage Sameera Madushan; Zhen, Ao Xuan; Hyun, Yu Jae; Ahn, Mee Jung; Kang, Hee Kyoung; Hyun, Jin Won

The Red Algae Compound 3-Bromo-4,5-dihydroxybenzaldehyde Protects Human Keratinocytes on Oxidative Stress-Related Molecules and Pathways Activated by UVB Irradiation

红藻化合物3-溴-4,5-二羟基苯甲醛可保护人类角质形成细胞免受UVB照射激活的氧化应激相关分子和通路的影响

期刊:Marine Drugs

影响因子:5.4

doi:10.3390/md15090268

Piao, Mei Jing; Kang, Kyoung Ah; Ryu, Yea Seong; Shilnikova, Kristina; Park, Jeong Eon; Hyun, Yu Jae; Zhen, Ao Xuan; Kang, Hee Kyoung; Koh, Young Sang; Ahn, Mee Jung; Hyun, Jin Won

Galangin Activates the ERK/AKT-Driven Nrf2 Signaling Pathway to Increase the Level of Reduced Glutathione in Human Keratinocytes

高良姜素激活ERK/AKT驱动的Nrf2信号通路，从而提高人角质形成细胞中还原型谷胱甘肽的水平

期刊:Biomolecules & Therapeutics

影响因子:3.2

doi:10.4062/biomolther.2016.112

Madduma Hewage, Susara Ruwan Kumara; Piao, Mei Jing; Kang, Kyoung Ah; Ryu, Yea Seong; Fernando, Pattage Madushan Dilhara Jayatissa; Oh, Min Chang; Park, Jeong Eon; Shilnikova, Kristina; Moon, Yu Jin; Shin, Dae O; Hyun, Jin Won

Reduced Autophagy in 5-Fluorouracil Resistant Colon Cancer Cells

5-氟尿嘧啶耐药结肠癌细胞自噬作用减弱

期刊:Biomolecules & Therapeutics

影响因子:3.2

doi:10.4062/biomolther.2016.069

Yao, Cheng Wen; Kang, Kyoung Ah; Piao, Mei Jing; Ryu, Yea Seong; Fernando, Pattage Madushan Dilhara Jayatissa; Oh, Min Chang; Park, Jeong Eon; Shilnikova, Kristina; Na, Soo-Young; Jeong, Seung Uk; Boo, Sun-Jin; Hyun, Jin Won

Hyperoside Induces Endogenous Antioxidant System to Alleviate Oxidative Stress

金丝桃苷诱导内源性抗氧化系统以减轻氧化应激

期刊:Journal of Cancer Prevention

影响因子:1.8

doi:10.15430/JCP.2016.21.1.41

Park, Ji Young; Han, Xia; Piao, Mei Jing; Oh, Min Chang; Fernando, Pattage Madushan Dilhara Jayatissa; Kang, Kyoung Ah; Ryu, Yea Seong; Jung, Uhee; Kim, In Gyu; Hyun, Jin Won

Secreted AZGP1 induced by 5-FU binds to PD-L1 and promotes apoptosis in cholangiocarcinoma.

5-FU诱导分泌的AZGP1与PD-L1结合，促进胆管癌细胞凋亡

Mutant PIK3CA as a negative predictive biomarker for treatment with a highly selective PIM1 inhibitor in human colon cancer

突变型PIK3CA作为高选择性PIM1抑制剂治疗人类结肠癌的阴性预测生物标志物

Mutation SVCT2 promotes cell proliferation, invasion and migration in colorectal cancer

SVCT2基因突变促进结直肠癌细胞增殖、侵袭和迁移

Marine Compound 3-bromo-4,5-dihydroxybenzaldehyde Protects Skin Cells against Oxidative Damage via the Nrf2/HO-1 Pathway

海洋化合物3-溴-4,5-二羟基苯甲醛通过Nrf2/HO-1通路保护皮肤细胞免受氧化损伤

Shikonin Exerts Cytotoxic Effects in Human Colon Cancers by Inducing Apoptotic Cell Death via the Endoplasmic Reticulum and Mitochondria-Mediated Pathways

紫草素通过内质网和线粒体介导的途径诱导细胞凋亡，从而对人结肠癌细胞发挥细胞毒性作用。

7,8-Dihydroxyflavone Protects High Glucose-Damaged Neuronal Cells against Oxidative Stress

7,8-二羟基黄酮可保护高葡萄糖损伤的神经元细胞免受氧化应激损伤

The Red Algae Compound 3-Bromo-4,5-dihydroxybenzaldehyde Protects Human Keratinocytes on Oxidative Stress-Related Molecules and Pathways Activated by UVB Irradiation

红藻化合物3-溴-4,5-二羟基苯甲醛可保护人类角质形成细胞免受UVB照射激活的氧化应激相关分子和通路的影响

Galangin Activates the ERK/AKT-Driven Nrf2 Signaling Pathway to Increase the Level of Reduced Glutathione in Human Keratinocytes

高良姜素激活ERK/AKT驱动的Nrf2信号通路，从而提高人角质形成细胞中还原型谷胱甘肽的水平

Reduced Autophagy in 5-Fluorouracil Resistant Colon Cancer Cells

5-氟尿嘧啶耐药结肠癌细胞自噬作用减弱

Hyperoside Induces Endogenous Antioxidant System to Alleviate Oxidative Stress

金丝桃苷诱导内源性抗氧化系统以减轻氧化应激