Genetic deletion or small-molecule inhibition of the arginine methyltransferase PRMT5 exhibit anti-tumoral activity in mouse models of MLL-rearranged AML
精氨酸甲基转移酶 PRMT5 的基因缺失或小分子抑制在 MLL 重排 AML 小鼠模型中表现出抗肿瘤活性
期刊:Leukemia
影响因子:12.8
doi:10.1038/leu.2017.206
S Kaushik, F Liu, K J Veazey, G Gao, P Das, L F Neves, K Lin, Y Zhong, Y Lu, V Giuliani, M T Bedford, S D Nimer, M A Santos
