Targeting glutamine metabolism in multiple myeloma enhances BIM binding to BCL-2 eliciting synthetic lethality to venetoclax
靶向多发性骨髓瘤中的谷氨酰胺代谢可增强 BIM 与 BCL-2 的结合，从而引发对维奈克拉的合成致死
期刊:Oncogene
影响因子:6.9
doi:10.1038/onc.2015.464
R Bajpai, S M Matulis, C Wei, A K Nooka, H E Von Hollen, S Lonial, L H Boise, M Shanmugam
