The Akt activation inhibitor TCN-P inhibits Akt phosphorylation by binding to the PH domain of Akt and blocking its recruitment to the plasma membrane
Akt 活化抑制剂 TCN-P 通过与 Akt 的 PH 结构域结合并阻止其募集到质膜来抑制 Akt 磷酸化
期刊:Cell Death and Differentiation
影响因子:13.7
doi:10.1038/cdd.2010.63
N Berndt, H Yang, B Trinczek, S Betzi, Z Zhang, B Wu, N J Lawrence, M Pellecchia, E Schönbrunn, J Q Cheng, S M Sebti